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4ate

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ate]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ATE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ate]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ATE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-porphyranase Beta-porphyranase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.178 3.2.1.178] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-porphyranase Beta-porphyranase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.178 3.2.1.178] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ate FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ate OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ate RCSB], [http://www.ebi.ac.uk/pdbsum/4ate PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ate FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ate OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ate RCSB], [http://www.ebi.ac.uk/pdbsum/4ate PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/D7GXG0_ZOBGA D7GXG0_ZOBGA]] Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6-sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6-sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.<ref>PMID:20376150</ref> <ref>PMID:22778272</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Beta-porphyranase]]
[[Category: Beta-porphyranase]]
[[Category: Zobellia galactanivorans]]
[[Category: Zobellia galactanivorans]]
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[[Category: Correc, G.]]
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[[Category: Correc, G]]
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[[Category: Czjzek, M.]]
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[[Category: Czjzek, M]]
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[[Category: Hehemann, J H.]]
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[[Category: Hehemann, J H]]
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[[Category: Jam, M.]]
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[[Category: Jam, M]]
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[[Category: Michel, G.]]
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[[Category: Michel, G]]
[[Category: Agar degradation]]
[[Category: Agar degradation]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 15:15, 25 December 2014

High resolution crystal structure of beta-porphyranase A from Zobellia galactanivorans

4ate, resolution 1.10Å

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