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4leb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4leb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LEB FirstGlance]. <br> | <table><tr><td colspan='2'>[[4leb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LEB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4le8|4le8]], [[4lee|4lee]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4le8|4le8]], [[4lee|4lee]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4leb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4leb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4leb RCSB], [http://www.ebi.ac.uk/pdbsum/4leb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4leb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4leb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4leb RCSB], [http://www.ebi.ac.uk/pdbsum/4leb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALS3_CANAX ALS3_CANAX]] Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cota, E | + | [[Category: Cota, E]] |
| - | [[Category: Garnett, J A | + | [[Category: Garnett, J A]] |
| - | [[Category: Lin, J | + | [[Category: Lin, J]] |
[[Category: Adhesin]] | [[Category: Adhesin]] | ||
[[Category: Biofilm formation]] | [[Category: Biofilm formation]] | ||
Revision as of 21:37, 24 December 2014
Structure of the Als3 adhesin from Candida albicans, residues 1-299 (mature sequence) in complex with hepta-threonine
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