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4bqv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bqv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BQV FirstGlance]. <br> | <table><tr><td colspan='2'>[[4bqv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BQV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8PW:(2S,4R)-N-(1-CYANOCYCLOPROPYL)-1-(1-METHYLCYCLOPROPANECARBONYL)-4-[4-(2,2,2-TRIFLUOROETHOXY)-2-(TRIFLUOROMETHYL)PHENYL]SULFONYLPYRROLIDINE-2-CARBOXAMIDE'>8PW</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8PW:(2S,4R)-N-(1-CYANOCYCLOPROPYL)-1-(1-METHYLCYCLOPROPANECARBONYL)-4-[4-(2,2,2-TRIFLUOROETHOXY)-2-(TRIFLUOROMETHYL)PHENYL]SULFONYLPYRROLIDINE-2-CARBOXAMIDE'>8PW</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bpv|4bpv]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bpv|4bpv]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqv RCSB], [http://www.ebi.ac.uk/pdbsum/4bqv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqv RCSB], [http://www.ebi.ac.uk/pdbsum/4bqv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
| - | [[Category: Banner, D W | + | [[Category: Banner, D W]] |
| - | [[Category: Benz, J | + | [[Category: Benz, J]] |
| - | [[Category: Gsell, B | + | [[Category: Gsell, B]] |
| - | [[Category: Haap, W | + | [[Category: Haap, W]] |
| - | [[Category: Ruf, A | + | [[Category: Ruf, A]] |
| - | [[Category: Stihle, M | + | [[Category: Stihle, M]] |
[[Category: Cysteine protease]] | [[Category: Cysteine protease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 06:09, 25 December 2014
MOUSE CATHEPSIN S WITH COVALENT LIGAND
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Categories: Cathepsin S | Banner, D W | Benz, J | Gsell, B | Haap, W | Ruf, A | Stihle, M | Cysteine protease | Hydrolase
