Dioxygenase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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'''Dioxygenase Intradiol family'''
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===''Dioxygenase Intradiol family''===
[[2pcd]] – PpPCD α,β + Fe+3 – ''Pseudomonas putida''<br />
[[2pcd]] – PpPCD α,β + Fe+3 – ''Pseudomonas putida''<br />
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[[2bux]] – AcPCD α,β (mutant) + Fe+3 <br />
[[2bux]] – AcPCD α,β (mutant) + Fe+3 <br />
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'''PCD complex with aromatic compound'''
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''PCD complex with aromatic compound''
[[3pcf]], [[3pch]], [[3pci]] – PpPCD α,β + Fe+3 + HB derivative<br />
[[3pcf]], [[3pch]], [[3pci]] – PpPCD α,β + Fe+3 + HB derivative<br />
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[[3lxv]], [[3mi5]], [[3t67]] – PpPCD α,β (mutant) + Fe+3 + catechol derivative<br />
[[3lxv]], [[3mi5]], [[3t67]] – PpPCD α,β (mutant) + Fe+3 + catechol derivative<br />
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'''Protocatechuate 4,5-dioxygenase (PCD)'''
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===Protocatechuate 4,5-dioxygenase (PCD)===
[[1b4u]] – SpPCD α,β + Fe+3 + DHB – ''Sphingomonas paucimobilis''<br />
[[1b4u]] – SpPCD α,β + Fe+3 + DHB – ''Sphingomonas paucimobilis''<br />
[[1bou]] – SpPCD α,β + Fe+3 <br />
[[1bou]] – SpPCD α,β + Fe+3 <br />
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'''Catechol 1,2-dioxygenase (CTD''')
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===Catechol 1,2-dioxygenase (CTD)===
[[1dlm]], [[1dlq]] – AcCTD + Fe+3 <br />
[[1dlm]], [[1dlq]] – AcCTD + Fe+3 <br />
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[[2xsv]], [[2xsr]] – ArCTD + Fe+3 + phosphoinositol derivative <br />
[[2xsv]], [[2xsr]] – ArCTD + Fe+3 + phosphoinositol derivative <br />
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'''Chlorocatechol 1,2-dioxygenase (CCTD)'''
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===Chlorocatechol 1,2-dioxygenase (CCTD)===
[[3th1]] – PpCCTD + Fe+3 <br />
[[3th1]] – PpCCTD + Fe+3 <br />
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[[2boy]] – RoCCTD + Fe+3 + benzhydroxamate<br />
[[2boy]] – RoCCTD + Fe+3 + benzhydroxamate<br />
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'''Catechol 2,3-dioxygenase (CTD)'''
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===Catechol 2,3-dioxygenase (CTD)===
[[2wl3]], [[2wl9]] - RoCTD + Fe+3 - ''Rhodococcus opacus'' <br />
[[2wl3]], [[2wl9]] - RoCTD + Fe+3 - ''Rhodococcus opacus'' <br />
[[3lm4]] – RoCTD + Fe+3 + H2O2<br />
[[3lm4]] – RoCTD + Fe+3 + H2O2<br />
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'''Hydroxyquinol 1,2-dioxygenase (HQD)'''
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===Hydroxyquinol 1,2-dioxygenase (HQD)===
[[1tmx]] – PpHQD + Fe+3 – ''Pimelobacter simplex''<br />
[[1tmx]] – PpHQD + Fe+3 – ''Pimelobacter simplex''<br />
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'''Nitrobenzene dioxygenase (NBDO)'''
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===Nitrobenzene dioxygenase (NBDO)===
[[2bmo]] – CtNBDO + Fe+3 + Fe2S2 <br />
[[2bmo]] – CtNBDO + Fe+3 + Fe2S2 <br />
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[[2bmr]] – CtNBDO + Fe+3 + Fe2S2 + nitrotoluene<br />
[[2bmr]] – CtNBDO + Fe+3 + Fe2S2 + nitrotoluene<br />
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'''α-ketoglutarate-dependent dioxygenase'''
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===α-ketoglutarate-dependent dioxygenase (Alkb)===
[[3t4h]], [[3t4v]], [[3t3y]] – EcAlkb + Fe+3 + inhibitor – ''Escherichia coli''<br />
[[3t4h]], [[3t4v]], [[3t3y]] – EcAlkb + Fe+3 + inhibitor – ''Escherichia coli''<br />
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[[4ie7]] – hFto + Zn+2 + rhein<br />
[[4ie7]] – hFto + Zn+2 + rhein<br />
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'''Alkb complex with DNA'''
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''Alkb complex with DNA''
[[3rzm]], [[3rzl]], [[3rzh]], [[3rzg]], [[3btz]] – hAlkb (mutant) + DNA<br />
[[3rzm]], [[3rzl]], [[3rzh]], [[3rzg]], [[3btz]] – hAlkb (mutant) + DNA<br />
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[[3o1v]], [[3o1u]], [[3o1t]], [[3t1s]] – hAlkb (mutant) + Fe+3 + succinate + DNA + inhibitor<br />
[[3o1v]], [[3o1u]], [[3o1t]], [[3t1s]] – hAlkb (mutant) + Fe+3 + succinate + DNA + inhibitor<br />
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'''Dioxygenase extradiol family'''
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===Dioxygenase extradiol family===
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'''Homoprotocatechuate 2,3-dioxygenase (HPCD)'''
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===Homoprotocatechuate 2,3-dioxygenase (HPCD)===
[[1f1r]], [[1f1u]] – AgHPCD + Mn+2 – ''Arthrobacter globiformis''<br />
[[1f1r]], [[1f1u]] – AgHPCD + Mn+2 – ''Arthrobacter globiformis''<br />
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[[4ghh]] – BfHPCD + Fe+2 + catechol derivative<br />
[[4ghh]] – BfHPCD + Fe+2 + catechol derivative<br />
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'''Catechol 2,3-dioxygenase (MPC)'''
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===Catechol 2,3-dioxygenase (MPC)===
[[1mpy]] – PpMPC + Fe+2 <br />
[[1mpy]] – PpMPC + Fe+2 <br />
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[[3hq0]] – PsMPC + Fe+3 + product<br />
[[3hq0]] – PsMPC + Fe+3 + product<br />
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'''Naphthalene 1,2-dioxygenase (NDO)'''
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===Naphthalene 1,2-dioxygenase (NDO)===
[[1ndo]], [[1o7h]], [[1o7w]] – PpNDO + Fe+3 + Fe2S2<br />
[[1ndo]], [[1o7h]], [[1o7w]] – PpNDO + Fe+3 + Fe2S2<br />
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[[4hkv]] – PsNDO + Fe+3 + Fe2S2 + benzamide<br />
[[4hkv]] – PsNDO + Fe+3 + Fe2S2 + benzamide<br />
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'''Dihydronaphthalene 1,2-dioxygenase (HNDO)'''
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===Dihydronaphthalene 1,2-dioxygenase (HNDO)===
[[2ehz]], [[2ei2]] – PsHNDO + Fe+2 <br />
[[2ehz]], [[2ei2]] – PsHNDO + Fe+2 <br />
[[2ei0]], [[2ei1]], [[2ei3]] – PsHNDO + Fe+2 + dihydroxybephenyl<br />
[[2ei0]], [[2ei1]], [[2ei3]] – PsHNDO + Fe+2 + dihydroxybephenyl<br />
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'''2,3-dihydroxybiphenyl 1,2-dioxygenase (DHBP)'''
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===2,3-dihydroxybiphenyl 1,2-dioxygenase (DHBP)===
[[1dhy]], [[1eil]], [[1eiq]], [[1eir]] – PsDHBP + Fe+3 <br />
[[1dhy]], [[1eil]], [[1eiq]], [[1eir]] – PsDHBP + Fe+3 <br />
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[[1kwc]] – PsDHBP (mutant) + dihydroxybephenyl<br />
[[1kwc]] – PsDHBP (mutant) + dihydroxybephenyl<br />
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'''Salicylate 1,2-dioxygenase (SDO)'''
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===Salicylate 1,2-dioxygenase (SDO)===
[[2phd]] – PssSDO + Fe+3 – ''Pseudaminobacter salicylatoxidans''<br />
[[2phd]] – PssSDO + Fe+3 – ''Pseudaminobacter salicylatoxidans''<br />
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[[3nw4]], [[4fag]] – PssSDO (mutant) + Fe+2 +gentisate<br />
[[3nw4]], [[4fag]] – PssSDO (mutant) + Fe+2 +gentisate<br />
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'''Biphenyl 1,2-dioxygenase (BDO)'''
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===Biphenyl 1,2-dioxygenase (BDO)===
[[3gzy]] – CtBDO + Fe+2 + Fe2S2 – ''Comamonas testosteroni''<br />
[[3gzy]] – CtBDO + Fe+2 + Fe2S2 – ''Comamonas testosteroni''<br />
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[[2gbx]] - SyBDO + Fe+2 + Fe2S2 + biphenyl <br />
[[2gbx]] - SyBDO + Fe+2 + Fe2S2 + biphenyl <br />
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'''Tryptophan 2,3-dioxygenase (TDO)'''
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===Tryptophan 2,3-dioxygenase (TDO)===
[[1yw0]] – XcTDO + Mg – ''Xanthomonas campestris''<br />
[[1yw0]] – XcTDO + Mg – ''Xanthomonas campestris''<br />
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[[2nox]] – CmTDO + heme – ''Cupriavidus metallidurans''<br />
[[2nox]] – CmTDO + heme – ''Cupriavidus metallidurans''<br />
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'''Cysteine dioxygenase type I (CysDO)'''
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===Cysteine dioxygenase type I (CysDO)===
[[2gh2]], [[4ieo]], [[4iep]], [[4ieq]], [[4ier]], [[4ies]], [[4iet]], [[4ieu]], [[4iev]], [[4iew]], [[4iex]], [[4iey]], [[4iez]], [[4jtn]], [[4jto]], [[4kwj]], [[4kwk]], [[4kwl]] – rCysDO + Fe+2 – rat <br />
[[2gh2]], [[4ieo]], [[4iep]], [[4ieq]], [[4ier]], [[4ies]], [[4iet]], [[4ieu]], [[4iev]], [[4iew]], [[4iex]], [[4iey]], [[4iez]], [[4jtn]], [[4jto]], [[4kwj]], [[4kwk]], [[4kwl]] – rCysDO + Fe+2 – rat <br />
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[[2ic1]] – hCysDO + Fe+2 + cysteine<br />
[[2ic1]] – hCysDO + Fe+2 + cysteine<br />
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'''4-hydroxyphenylpyruvate dioxygenase (HPPD)'''
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===4-hydroxyphenylpyruvate dioxygenase (HPPD)===
[[1cjx]] – HPPD + Fe+2 – ''Pseudomonas fluorescens''<br />
[[1cjx]] – HPPD + Fe+2 – ''Pseudomonas fluorescens''<br />
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[[1sp8]] – HPPD + Fe+2 – corn<br />
[[1sp8]] – HPPD + Fe+2 – corn<br />
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'''Quercetin 2,3-dioxygenase (QDO)'''
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===Quercetin 2,3-dioxygenase (QDO)===
[[1juh]] – AjQDO + Cu+2 – ''Aspergillus japonicus''<br />
[[1juh]] – AjQDO + Cu+2 – ''Aspergillus japonicus''<br />
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[[1h1m]] – AjQDO + Cu+2 + kaempferol<br />
[[1h1m]] – AjQDO + Cu+2 + kaempferol<br />
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'''Taurine/α-ketoglutarate dioxygenase (TauD)'''
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===Taurine/α-ketoglutarate dioxygenase (TauD)===
[[1gqw]], [[1gy9]], [[1os7]] – EcTauD + Fe+2 + taurine + oxoglutarate <br />
[[1gqw]], [[1gy9]], [[1os7]] – EcTauD + Fe+2 + taurine + oxoglutarate <br />
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[[4j5i]] – HAD + Fe+3 – ''Mycobacterium smegmatis''<br />
[[4j5i]] – HAD + Fe+3 – ''Mycobacterium smegmatis''<br />
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'''3-hydroxyanthranilate 3,4-dioxygenase (HAD)'''
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===3-hydroxyanthranilate 3,4-dioxygenase (HAD)===
[[1yfu]] – CmHAD + Fe+3<br />
[[1yfu]] – CmHAD + Fe+3<br />
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[[3fe5]] – HAD + Fe+3 - bovine<br />
[[3fe5]] – HAD + Fe+3 - bovine<br />
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'''Carbazole 1,9a-dioxygenase (CDO)'''
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===Carbazole 1,9a-dioxygenase (CDO)===
[[1vck]] – HAD ferredoxin component + Fe+3 + Fe2S2 – ''Pseudomonas resinovorans''<br />
[[1vck]] – HAD ferredoxin component + Fe+3 + Fe2S2 – ''Pseudomonas resinovorans''<br />
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[[3vmi]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole + O2<br />
[[3vmi]] – JaHAD ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole + O2<br />
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'''Homogentisate 1,2-dioxygenase (HGDO)'''
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===Homogentisate 1,2-dioxygenase (HGDO)===
[[1ey2]] – hHGDO + Fe+2 <br />
[[1ey2]] – hHGDO + Fe+2 <br />

Revision as of 10:38, 17 August 2014

Structure of protocatechuate 3,4-dioxygenase with Fe+3 complex with dihydroxybenzoate (PDB entry 1eob)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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