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4qfs

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'''Unreleased structure'''
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==Structure of AMPK in complex with Br2-A769662core activator and STAUROSPORINE inhibitor==
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<StructureSection load='4qfs' size='340' side='right' caption='[[4qfs]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
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The entry 4qfs is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4qfs]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QFS FirstGlance]. <br>
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Authors: Calabrese, M.F., Kurumbail, R.G.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=32H:2-BROMO-3-(4-BROMOPHENYL)-4-HYDROXY-6-OXO-6,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE'>32H</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STU:STAUROSPORINE'>STU</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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Description:
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qfg|4qfg]], [[4qfr|4qfr]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qfs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qfs RCSB], [http://www.ebi.ac.uk/pdbsum/4qfs PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Calabrese, M F.]]
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[[Category: Kurumbail, R G.]]
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[[Category: Ampk]]
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[[Category: Cbm]]
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[[Category: Kinase]]
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[[Category: Signaling protein-inhibitor-activator complex]]

Revision as of 02:48, 7 August 2014

Structure of AMPK in complex with Br2-A769662core activator and STAUROSPORINE inhibitor

4qfs, resolution 3.55Å

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