4lpz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4lpz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LPZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4lpz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LPZ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x0o|1x0o]], [[4eq1|4eq1]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x0o|1x0o]], [[4eq1|4eq1]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lpz RCSB], [http://www.ebi.ac.uk/pdbsum/4lpz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lpz RCSB], [http://www.ebi.ac.uk/pdbsum/4lpz PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ARNT_HUMAN ARNT_HUMAN]] Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Gardner, K H | + | [[Category: Gardner, K H]] |
| - | [[Category: Guo, Y | + | [[Category: Guo, Y]] |
| - | [[Category: Scheuermann, T H | + | [[Category: Scheuermann, T H]] |
[[Category: Pas domain coiled coil]] | [[Category: Pas domain coiled coil]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 17:59, 25 December 2014
ARNT transcription factor/coactivator complex
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