1cwc
From Proteopedia
(Difference between revisions)
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|PDB= 1cwc |SIZE=350|CAPTION= <scene name='initialview01'>1cwc</scene>, resolution 1.86Å | |PDB= 1cwc |SIZE=350|CAPTION= <scene name='initialview01'>1cwc</scene>, resolution 1.86Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB]</span> | ||
}} | }} | ||
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[[Category: complex (isomerase/immunosuppressant)]] | [[Category: complex (isomerase/immunosuppressant)]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:29:50 2008'' |
Revision as of 16:29, 30 March 2008
| |||||||
| , resolution 1.86Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , | ||||||
| Gene: | CYCLOPHILIN (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN
About this Structure
1CWC is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain., Papageorgiou C, Florineth A, Mikol V, J Med Chem. 1994 Oct 28;37(22):3674-6. PMID:7966126
Page seeded by OCA on Sun Mar 30 19:29:50 2008
