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Serpin

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* Ser A3 is α 1-antichymotrypsin.<br />
* Ser A3 is α 1-antichymotrypsin.<br />
* Ser E1 is plasminogen activator inhibitor 1.
* Ser E1 is plasminogen activator inhibitor 1.
 +
</StructureSection>
==3D structures of serpin==
==3D structures of serpin==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Ser===
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*Serpin
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[[1mtp]], [[1sng]] – Ser – ''Thermobifida fusca''
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**[[1mtp]], [[1sng]] – Ser – ''Thermobifida fusca''
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===Ser A1===
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*Serpin A1see [[Alpha-1-antitrypsin]]
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[[Alpha-1-antitrypsin]]
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*Serpin A3 (α 1-antichymotrypsin)
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===Ser A3 (α 1-antichymotrypsin)===
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**[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br />
 +
**[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br />
 +
**[[1yxa]] – Ser-A3N - mouse<br />
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[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br />
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*Serpin A5
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[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br />
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-
[[1yxa]] – Ser-A3N - mouse<br />
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===Ser A5===
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**[[2ol2]] – hSer-A5<br />
 +
**[[3dy0]] – hSer-A5 + heparin
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[[2ol2]] – hSer-A5<br />
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*Serpin A6 see [[Corticosteroid-binding globulin]]
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[[3dy0]] – hSer-A5 + heparin
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===Ser A6===
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*Serpin A7
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[[Corticosteroid-binding globulin]]
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**[[2riv]] – hSer-A7<br />
 +
**[[2riw]] – hSer-A7 + thyroxine<br />
 +
**[[2xn3]] – hSer-A7 + mefenamic acid<br />
 +
**[[2xn5]] – hSer-A7 + furosemide<br />
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**[[2xn6]], [[2xn7]] – hSer-A7 + thyroxine-fluoresein
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===Ser A7===
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*Serpin A8
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[[2riv]] – hSer-A7<br />
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**[[2jp8]] – hSer-A8 – NMR<br />
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[[2riw]] – hSer-A7 + thyroxine<br />
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**[[2wxw]] – hSer-A8<br />
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[[2xn3]] – hSer-A7 + mefenamic acid<br />
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**[[2x0b]] – hSer-A8 + renin<br />
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[[2xn5]] – hSer-A7 + furosemide<br />
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**[[2wxx]], [[2wxy]], [[2wy0]] – Ser-A8 – mouse<br />
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[[2xn6]], [[2xn7]] – hSer-A7 + thyroxine-fluoresein
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**[[2wxz]], [[2wy1]] – rSer-A8
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===Ser A8===
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*Serpin A10
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[[2jp8]] – hSer-A8 – NMR<br />
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**[[3h5c]], [[3f1s]] – hSer-A10 + vitamin K-dependent protein Z
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[[2wxw]] – hSer-A8<br />
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[[2x0b]] – hSer-A8 + renin<br />
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[[2wxx]], [[2wxy]], [[2wy0]] – Ser-A8 – mouse<br />
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[[2wxz]], [[2wy1]] – rSer-A8
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===Ser A10===
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*Serpin A12
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[[3h5c]], [[3f1s]] – hSer-A10 + vitamin K-dependent protein Z
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**[[4if8]] – hSer-A12<br />
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===Ser A12===
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*Serpin B1 (leukocyte elastase inhibitor)
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[[4if8]] – hSer-A12<br />
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**[[1hle]] – Ser-B1 – horse <br />
 +
**[[4ga7]] – hSer-B1 (mutant) <br />
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===Ser B1 (leukocyte elastase inhibitor)===
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*Serpin B3
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[[1hle]] – Ser-B1 – horse <br />
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**[[2zv6]] – hSer-B3
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[[4ga7]] – hSer-B1 (mutant) <br />
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===Ser B3===
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*Serpin B5 (Maspin)
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[[2zv6]] – hSer-B3
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**[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br />
 +
**[[1xqj]] – hSer-B5 (mutant) <br />
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===Ser B5 (Maspin)===
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*Serpin C1 see [[Antithrombin]]
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[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br />
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*Serpin E1 see [[Plasminogen activator inhibitor]]
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[[1xqj]] – hSer-B5 (mutant) <br />
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===Ser C1===
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*Serpin E2
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[[Antithrombin]]
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**[[4dy0]] – hSer-E2 + heparin
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===Ser E1===
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*Serpin-I1
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[[Plasminogen activator inhibitor]]
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**[[3fgq]], [[2f02]], [[3f5n]] – hSer-I1
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===Ser E2===
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*Serpin K
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[[4dy0]] – hSer-E2 + heparin
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**[[1sek]] – ThSer-K – Tobacco hornworm
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===Ser-I1===
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*Serpin 1
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[[3fgq]], [[2f02]], [[3f5n]] – hSer-I1
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**[[1k9o]] – ThSer-1 (mutant) + trypsin II<br />
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**[[3le2]] – Ser-1 – ''Arabidopsis thaliana''
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===Ser K===
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*Serpin 2
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[[1sek]] – ThSer-K – Tobacco hornworm
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-
 
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===Ser 1===
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-
 
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[[1k9o]] – ThSer-1 (mutant) + trypsin II<br />
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[[3le2]] – Ser-1 – ''Arabidopsis thaliana''
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-
 
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===Ser 2===
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[[1m93]] – Ser-2 – Cowpox virus<br />
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-
[[3nda]] – Ser-2 – Sheep tick<br />
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[[3pzf]] – Ser-2 – malaria mosquito
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 +
**[[1m93]] – Ser-2 – Cowpox virus<br />
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**[[3nda]] – Ser-2 – Sheep tick<br />
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**[[3pzf]] – Ser-2 – malaria mosquito
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}}
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</StructureSection>
 
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:03, 10 December 2014

Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry 3ndd)

Drag the structure with the mouse to rotate

3D structures of serpin

Updated on 10-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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