This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4oql
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4oql]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OQL FirstGlance]. <br> | <table><tr><td colspan='2'>[[4oql]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OQL FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F2U:2-DEOXY-5-ETHYNYL-2,2-DIFLUOROURIDINE'>F2U</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F2U:2-DEOXY-5-ETHYNYL-2,2-DIFLUOROURIDINE'>F2U</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oqm|4oqm]], [[4oqn|4oqn]], [[4oqx|4oqx]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oqm|4oqm]], [[4oqn|4oqn]], [[4oqx|4oqx]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oql RCSB], [http://www.ebi.ac.uk/pdbsum/4oql PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oql RCSB], [http://www.ebi.ac.uk/pdbsum/4oql PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KITH_HHV11 KITH_HHV11]] In latent infection, may allow the virus to be reactivated and to grow in cells lacking a high concentration of phosphorylated nucleic acid precursors, such as nerve cells that do not replicate their genome (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 23: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Thymidine kinase]] | [[Category: Thymidine kinase]] | ||
| - | [[Category: Luedtke, N | + | [[Category: Luedtke, N]] |
| - | [[Category: Neef, A B | + | [[Category: Neef, A B]] |
| - | [[Category: Pernot, L | + | [[Category: Pernot, L]] |
| - | [[Category: Perozzo, R | + | [[Category: Perozzo, R]] |
| - | [[Category: Scapozza, L | + | [[Category: Scapozza, L]] |
| - | [[Category: Westermaier, Y | + | [[Category: Westermaier, Y]] |
[[Category: 5-ethynyluridine nucleoside derivative]] | [[Category: 5-ethynyluridine nucleoside derivative]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Dna synthesis]] | [[Category: Dna synthesis]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Thymidine kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 23:16, 24 December 2014
Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU
| |||||||||||
