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4qu6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4qu6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QU6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4qu6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QU6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qu6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qu6 RCSB], [http://www.ebi.ac.uk/pdbsum/4qu6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qu6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qu6 RCSB], [http://www.ebi.ac.uk/pdbsum/4qu6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GRSF1_HUMAN GRSF1_HUMAN]] Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences.<ref>PMID:23473033</ref> <ref>PMID:23473034</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: TCELL, Partnership for T-Cell Biology | + | [[Category: TCELL, Partnership for T-Cell Biology]] |
[[Category: Jcsg]] | [[Category: Jcsg]] | ||
| - | [[Category: Joint center for structural genomic]] | ||
[[Category: Pf14259 family]] | [[Category: Pf14259 family]] | ||
| - | [[Category: Protein structure initiative]] | + | [[Category: PSI, Protein structure initiative]] |
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Rna binding domain]] | [[Category: Rna binding domain]] | ||
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[[Category: Rna-binding protein]] | [[Category: Rna-binding protein]] | ||
[[Category: Rrm_6]] | [[Category: Rrm_6]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 08:38, 25 December 2014
Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 1.75 A resolution
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