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Aminopeptidase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Cysteine aminopeptidase===
+
*Cysteine aminopeptidase
-
[[3pw3]] – PdCys-AP – ''Parabacteroides distasonis''
+
**[[3pw3]] – PdCys-AP – ''Parabacteroides distasonis''
-
===Glutamic acid aminopeptidase===
+
*Glutamic acid aminopeptidase
-
[[2wyr]] – PhGlu-AP+Co – ''Pyrococcus horikoshii''<br />
+
**[[2wyr]] – PhGlu-AP+Co – ''Pyrococcus horikoshii''<br />
-
[[3kl9]] – SpGlu-AP – ''Streptococcus pneumoniae''<br />
+
**[[3kl9]] – SpGlu-AP – ''Streptococcus pneumoniae''<br />
-
[[4kx7]] – hGlu-AP + Zn – human<br />
+
**[[4kx7]] – hGlu-AP + Zn – human<br />
-
[[4kx8]], [[4kxb]] – hGlu-AP + Zn + statin derivative<br />
+
**[[4kx8]], [[4kxb]] – hGlu-AP + Zn + statin derivative<br />
-
[[4kx9]], [[4kxa]], [[4kxc]], [[4kxd]] – hGlu-AP + Zn + amino acid<br />
+
**[[4kx9]], [[4kxa]], [[4kxc]], [[4kxd]] – hGlu-AP + Zn + amino acid<br />
-
===Alanine aminopeptidase===
+
*Alanine aminopeptidase
-
[[3ebg]] – PfAla-AP - ''Plasmodium falciparum''<br />
+
**[[3ebg]] – PfAla-AP - ''Plasmodium falciparum''<br />
-
[[3ebh]] - PfAla-AP+bestatin<br />
+
**[[3ebh]] - PfAla-AP+bestatin<br />
-
[[3ebi]] - PfAla-AP+dipeptide analog<br />
+
**[[3ebi]] - PfAla-AP+dipeptide analog<br />
-
[[4fke]] – pAla-AP + Zn – pig<br />
+
**[[4fke]] – pAla-AP + Zn – pig<br />
-
[[4fkh]] – pAla-AP + Zn + alanine<br />
+
**[[4fkh]] – pAla-AP + Zn + alanine<br />
-
[[4h5h]], [[4hol]], [[4naq]], [[4nz8]] – pAla-AP + Zn + polyalanine<br />
+
**[[4h5h]], [[4hol]], [[4naq]], [[4nz8]] – pAla-AP + Zn + polyalanine<br />
-
[[4hom]] – pAla-AP + Zn + substance P<br />
+
**[[4hom]] – pAla-AP + Zn + substance P<br />
-
[[4fkk]] – pAla-AP + Zn + bestatin<br />
+
**[[4fkk]] – pAla-AP + Zn + bestatin<br />
-
[[4f5c]] – pAla-AP + PRCV spike protein + Zn<br />
+
**[[4f5c]] – pAla-AP + PRCV spike protein + Zn<br />
-
[[4fyq]] - hAla-AP + Zn <br />
+
**[[4fyq]] - hAla-AP + Zn <br />
-
[[4fyr]] - hAla-AP + Zn + bestatin<br />
+
**[[4fyr]] - hAla-AP + Zn + bestatin<br />
-
[[4fys]] - hAla-AP + Zn + angiotensin<br />
+
**[[4fys]] - hAla-AP + Zn + angiotensin<br />
-
[[4fyt]] - hAla-AP + Zn + amastatin<br />
+
**[[4fyt]] - hAla-AP + Zn + amastatin<br />
-
[[3ked]] – EcAPN+2,4-diaminobutyric acid – ''Escherichia coli''<br />
+
**[[3ked]] – EcAPN+2,4-diaminobutyric acid – ''Escherichia coli''<br />
-
[[2hpo]], [[2dq6]], [[3puu]] – EcAPN<br />
+
**[[2hpo]], [[2dq6]], [[3puu]] – EcAPN<br />
-
[[2hpt]], [[2dqm]] – EcAPN+bestatin<br />
+
**[[2hpt]], [[2dqm]] – EcAPN+bestatin<br />
-
[[2zxg]] – EcAPN+transition state analog<br />
+
**[[2zxg]] – EcAPN+transition state analog<br />
-
[[3b2p]], [[3b2x]], [[3b34]], [[3b37]], [[3b3b]], [[3qjx]] – EcAPN+amino acid<br />
+
**[[3b2p]], [[3b2x]], [[3b34]], [[3b37]], [[3b3b]], [[3qjx]] – EcAPN+amino acid<br />
-
[[2gtq]] – APN – ''Neisseria meningitides''
+
**[[2gtq]] – APN – ''Neisseria meningitides''
-
===Proline aminopeptidase===
+
*Proline aminopeptidase
-
[[3ovk]] – Xaa Pro-AP – ''Streptococcus pyogenes''<br />
+
**[[3ovk]] – Xaa Pro-AP – ''Streptococcus pyogenes''<br />
-
[[3il0]] - Xaa Pro-AP – ''Streptococcus thermophilus''<br />
+
**[[3il0]] - Xaa Pro-AP – ''Streptococcus thermophilus''<br />
-
[[2v3x]], [[2v3y]], [[2v3z]] - Xaa EcPro-AP (mutant)+tripeptide<br />
+
**[[2v3x]], [[2v3y]], [[2v3z]] - Xaa EcPro-AP (mutant)+tripeptide<br />
-
[[1w7v]], [[2bh3]] - Xaa EcPro-AP+Zn+Mg+polypeptide<br />
+
**[[1w7v]], [[2bh3]] - Xaa EcPro-AP+Zn+Mg+polypeptide<br />
-
[[2bn7]] - Xaa EcPro-AP+Zn+Mg+Mn+polypeptide<br />
+
**[[2bn7]] - Xaa EcPro-AP+Zn+Mg+Mn+polypeptide<br />
-
[[2bha]], [[2bhd]] - Xaa EcPro-AP+Mg+polypeptide<br />
+
**[[2bha]], [[2bhd]] - Xaa EcPro-AP+Mg+polypeptide<br />
-
[[1a16]] - Xaa EcPro-AP+Mn+polypeptide<br />
+
**[[1a16]] - Xaa EcPro-AP+Mn+polypeptide<br />
-
[[1wbq]], [[2bhb]] - Xaa EcPro-AP+Zn+Mg<br />
+
**[[1wbq]], [[2bhb]] - Xaa EcPro-AP+Zn+Mg<br />
-
[[2bhc]] - Xaa EcPro-AP+Na+Mg<br />
+
**[[2bhc]] - Xaa EcPro-AP+Na+Mg<br />
-
[[1wl6]] - Xaa EcPro-AP+Mg<br />
+
**[[1wl6]] - Xaa EcPro-AP+Mg<br />
-
[[1wl9]], [[1m35]], [[1jaw]] - Xaa EcPro-AP+Mn<br />
+
**[[1wl9]], [[1m35]], [[1jaw]] - Xaa EcPro-AP+Mn<br />
-
[[1wlr]] - Xaa EcPro-AP<br />
+
**[[1wlr]] - Xaa EcPro-AP<br />
-
[[2bws]], [[2bwt]], [[2bwu]], [[2bwv]], [[2bww]], [[2bwx]], [[2bwy]] - Xaa EcPro-AP (mutant)<br />
+
**[[2bws]], [[2bwt]], [[2bwu]], [[2bwv]], [[2bww]], [[2bwx]], [[2bwy]] - Xaa EcPro-AP (mutant)<br />
-
[[1w2m]] - Xaa EcPro-AP+Ca<br />
+
**[[1w2m]] - Xaa EcPro-AP+Ca<br />
-
[[1n51]] – Xaa EcPro-AP+apstatin<br />
+
**[[1n51]] – Xaa EcPro-AP+apstatin<br />
-
[[3ig4]] - Xaa Pro-AP+ Mn – ''Bacillus anthracis''<br />
+
**[[3ig4]] - Xaa Pro-AP+ Mn – ''Bacillus anthracis''<br />
-
[[4fkc]] – Xaa Pro-AP + Cd – ''Thermococcus sibiricus''<br />
+
**[[4fkc]] – Xaa Pro-AP + Cd – ''Thermococcus sibiricus''<br />
-
[[2zsg]] – X TmPro-AP – ''Thermatoga maritima''<br />
+
**[[2zsg]] – X TmPro-AP – ''Thermatoga maritima''<br />
-
[[3ctz]] – X hPro-AP <br />
+
**[[3ctz]] – X hPro-AP <br />
-
[[1x2b]], [[1x2e]], [[1wm1]] – SmPro-AP + inhibitor – ''Serratia marcescens''<br />
+
**[[1x2b]], [[1x2e]], [[1wm1]] – SmPro-AP + inhibitor – ''Serratia marcescens''<br />
-
[[1qtr]] – SmPro-AP<br />
+
**[[1qtr]] – SmPro-AP<br />
-
[[1xqv]] – TaPro-AP (mutant) – ''Thermoplasma acidophilum''<br />
+
**[[1xqv]] – TaPro-AP (mutant) – ''Thermoplasma acidophilum''<br />
-
[[1xqw]], [[1xqx]], [[1xqy]], [[1xrl]], [[1xrm]], [[1xrn]], [[1xro]], [[1xrp]], [[1xrq]], [[1xrr]] – TaPro-AP+polypeptide<br />
+
**[[1xqw]], [[1xqx]], [[1xqy]], [[1xrl]], [[1xrm]], [[1xrn]], [[1xro]], [[1xrp]], [[1xrq]], [[1xrr]] – TaPro-AP+polypeptide<br />
-
[[3azo]] – SmPro-AP – ''Streptomyces morookaensis''<br />
+
**[[3azo]] – SmPro-AP – ''Streptomyces morookaensis''<br />
-
[[3azp]] - SmPro-AP (mutant)<br />
+
**[[3azp]] - SmPro-AP (mutant)<br />
-
[[3azq]] - SmPro-AP (mutant) + PGG<br />
+
**[[3azq]] - SmPro-AP (mutant) + PGG<br />
-
[[1lns]] – Pro-dipeptidyl-AP – ''Lactococcus lactis''<br />
+
**[[1lns]] – Pro-dipeptidyl-AP – ''Lactococcus lactis''<br />
-
[[2z3w]] – PgPro-tripeptidyl-AP (mutant) – ''Porphyromonas gingivalis''<br />
+
**[[2z3w]] – PgPro-tripeptidyl-AP (mutant) – ''Porphyromonas gingivalis''<br />
-
[[2z3z]] – PgPro-tripeptidyl-AP (mutant) + inhibitor<br />
+
**[[2z3z]] – PgPro-tripeptidyl-AP (mutant) + inhibitor<br />
-
===Leucine aminopeptidase===
+
*Leucine aminopeptidase
-
[[3jru]] – Leu-AP – ''Xanthomonas oryzae''<br />
+
**[[3jru]] – Leu-AP – ''Xanthomonas oryzae''<br />
-
[[2hc9]], [[2hb6]] – Leu-AP – ''Caenorhabditis elegans''<br />
+
**[[2hc9]], [[2hb6]] – Leu-AP – ''Caenorhabditis elegans''<br />
-
[[2ewb]] – bLeu-AP+zofenoprilat – bovine<br />
+
**[[2ewb]] – bLeu-AP+zofenoprilat – bovine<br />
-
[[1lam]], [[1lap]] – bLue-AP<br />
+
**[[1lam]], [[1lap]] – bLue-AP<br />
-
[[1bpm]], [[1bpn]] – bLue-AP+Zn+Mg<br />
+
**[[1bpm]], [[1bpn]] – bLue-AP+Zn+Mg<br />
-
[[2j9a]] - bLue-AP+Zn + inhibitor<br />
+
**[[2j9a]] - bLue-AP+Zn + inhibitor<br />
-
[[1lan]], [[1lcp]] – bLue-AP+leucine derivative<br />
+
**[[1lan]], [[1lcp]] – bLue-AP+leucine derivative<br />
-
[[1bll]] – bLue-AP+amastatin<br />
+
**[[1bll]] – bLue-AP+amastatin<br />
-
[[2xdt]], [[2yd0]] – hLeu-AP soluble domain <br />
+
**[[3rjo]] - hLeu-AP peptide-binding domain<br />
-
[[3rjo]] - hLeu-AP peptide-binding domain<br />
+
**[[3mdj]] - hLeu-AP soluble domain + inhibitor<br />
-
[[3mdj]] - hLeu-AP soluble domain + inhibitor<br />
+
**[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – ''Pseudomonas putida''<br />
-
[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – ''Pseudomonas putida''<br />
+
**[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br />
-
[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br />
+
**[[3fh4]], [[1rtq]], [[2dea]] – VpLeu-AP – Vibrio proteolyticus<br />
-
[[3fh4]], [[1rtq]], [[2dea]] – VpLeu-AP – Vibrio proteolyticus<br />
+
**[[3b35]], [[3b3t]], [[3b3v]], [[2anp]] - VpLeu-AP (mutant)<br />
-
[[3b35]], [[3b3t]], [[3b3v]], [[2anp]] - VpLeu-AP (mutant)<br />
+
**[[3b3c]], [[3b3s]], [[3b3w]] - VpLeu-AP (mutant)+Leu derivative<br />
-
[[3b3c]], [[3b3s]], [[3b3w]] - VpLeu-AP (mutant)+Leu derivative<br />
+
**[[3b7i]] - VpLeu-AP (mutant)+Leu<br />
-
[[3b7i]] - VpLeu-AP (mutant)+Leu<br />
+
**[[1ft7]] - VpLeu-AP +Leu derivative<br />
-
[[1ft7]] - VpLeu-AP +Leu derivative<br />
+
**[[3vh9]] - VpLeu-AP + 8-quinolinol<br />
-
[[3vh9]] - VpLeu-AP + 8-quinolinol<br />
+
**[[2nyq]], [[2iq6]] – VpLeu-AP+polypeptide<br />
-
[[2nyq]], [[2iq6]] – VpLeu-AP+polypeptide<br />
+
**[[1lok]] – VpLeu-AP+Tris<br />
-
[[1lok]] – VpLeu-AP+Tris<br />
+
**[[2prq]] – VpLeu-AP+Co<br />
-
[[2prq]] – VpLeu-AP+Co<br />
+
**[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br />
-
[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br />
+
**[[1gyt]] – EcLeu-AP<br />
-
[[1gyt]] – EcLeu-AP<br />
+
**[[3qnf]] – hLeu-AP 1<br />
-
[[3qnf]] – hLeu-AP 1<br />
+
**[[3t8w]], [[4k3n]] – PfLeu-AP + Zn + inhibitor – ''Plasmodium falciparum''<br />
-
[[3t8w]], [[4k3n]] – PfLeu-AP + Zn + inhibitor – ''Plasmodium falciparum''<br />
+
**[[3tc8]] - PdLeu-AP + Zn<br />
-
[[3tc8]] - PdLeu-AP + Zn<br />
+
**[[4fuu]] - Leu-AP + Zn – ''Bacterioides thetaiotaomicron''<br />
-
[[4fuu]] - Leu-AP + Zn – ''Bacterioides thetaiotaomicron''<br />
+
**[[4ksi]] – Leu-AP + Mg – tomato<br />
-
[[4ksi]] – Leu-AP + Mg – tomato<br />
+
-
===Methionine aminopeptidase===
+
*Methionine aminopeptidase
-
[[3mr1]], [[3mx6]] – Met-AP+Mn – ''Rickettsia prowazekii''<br />
+
**[[3mr1]], [[3mx6]] – Met-AP+Mn – ''Rickettsia prowazekii''<br />
-
[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PfMet-AP+Co – ''Pyrococcus furiosus''<br />
+
**[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PfMet-AP+Co – ''Pyrococcus furiosus''<br />
-
[[1wkm]] - PfMet-AP+Mn<br />
+
**[[1wkm]] - PfMet-AP+Mn<br />
-
[[4fo7]] - PaMet-AP+Mn – ''Pseudomonas aeruginosa''<br />
+
**[[4fo7]] - PaMet-AP+Mn – ''Pseudomonas aeruginosa''<br />
-
[[4fo8]] - PaMet-AP+Mn + Met <br />
+
**[[4fo8]] - PaMet-AP+Mn + Met <br />
-
[[4hxx]], [[4iu6]] - hMet-AP+ Co + pyrimidine derivative<br />
+
**[[4hxx]], [[4iu6]] - hMet-AP+ Co + pyrimidine derivative<br />
-
[[3iu7]] – MtMet-AP+Mn +A02 – ''Mycobacterium tuberculosis''<br />
+
**[[3iu7]] – MtMet-AP+Mn +A02 – ''Mycobacterium tuberculosis''<br />
-
[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br />
+
**[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br />
-
[[1yj3]], [[3ror]] - MtMet-AP+Co<br />
+
**[[1yj3]], [[3ror]] - MtMet-AP+Co<br />
-
[[3pka]] - MtMet-AP+Mn<br />
+
**[[3pka]] - MtMet-AP+Mn<br />
-
[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br />
+
**[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br />
-
[[3tav]] – Met-AP + Mg – ''Mycobacterium abscessus''< br />
+
**[[3tav]] – Met-AP + Mg – ''Mycobacterium abscessus''< br />
-
[[1y1n]] - MtMet-AP+K<br />
+
**[[1y1n]] - MtMet-AP+K<br />
-
[[4idy]], [[4iec]] - MtMet-AP+K + hydroxyethyl disulfide<br />
+
**[[4idy]], [[4iec]] - MtMet-AP+K + hydroxyethyl disulfide<br />
-
[[4if7]] - MtMet-AP+K + homocysteinemethyl disulfide<br />
+
**[[4if7]] - MtMet-AP+K + homocysteinemethyl disulfide<br />
-
[[3fm3]] – EncMet-AP – ''Encephalitozoon cuniculi''<br />
+
**[[3fm3]] – EncMet-AP – ''Encephalitozoon cuniculi''<br />
-
[[3fmq]], [[3fmr]] - EncMet-AP+angiogenesis inhibitor<br />
+
**[[3fmq]], [[3fmr]] - EncMet-AP+angiogenesis inhibitor<br />
-
[[3d27]], [[2q92]], [[2q93]], [[2q94]], [[2q95]], [[2q96]], [[2p98]], [[2p99]], [[2p9a]], [[2gu4]], [[2gu5]], [[2gu6]], [[2evc]], [[2evm]], [[2evo]], [[2bbv]], [[1xnz]], [[4a6v]], [[4a6w]], [[2bb7]] – EcMet-AP+Mn+inhibitor<br />
+
**[[3d27]], [[2q92]], [[2q93]], [[2q94]], [[2q95]], [[2q96]], [[2p98]], [[2p99]], [[2p9a]], [[2gu4]], [[2gu5]], [[2gu6]], [[2evc]], [[2evm]], [[2evo]], [[2bbv]], [[1xnz]], [[4a6v]], [[4a6w]], [[2bb7]] – EcMet-AP+Mn+inhibitor<br />
-
[[2gg0]], [[2gg2]], [[2gg3]], [[2gg5]], [[2gg7]], [[2gg8]], [[2gg9]], [[2ggb]], [[2ggc]] - EcMet-AP+Co+inhibitor<br />
+
**[[2gg0]], [[2gg2]], [[2gg3]], [[2gg5]], [[2gg7]], [[2gg8]], [[2gg9]], [[2ggb]], [[2ggc]] - EcMet-AP+Co+inhibitor<br />
-
[[1c21]], [[1c22]], [[1c23]], [[1c24]] - EcMet-AP +Co + methionine derivative<br />
+
**[[1c21]], [[1c22]], [[1c23]], [[1c24]] - EcMet-AP +Co + methionine derivative<br />
-
[[1c27]] - EcMet-AP +Co +norleucine<br />
+
**[[1c27]] - EcMet-AP +Co +norleucine<br />
-
[[3tb5]] – Met-AP – ''Enterococcus faecalis''<br />
+
**[[3tb5]] – Met-AP – ''Enterococcus faecalis''<br />
-
[[2ea2]], [[2ea4]], [[2ga2]], [[2nq6]], [[2nq7]], [[1yw7]], [[1yw8]], [[1yw9]] - hMet-AP+Mn+inhibitor<br />
+
**[[2ea2]], [[2ea4]], [[2ga2]], [[2nq6]], [[2nq7]], [[1yw7]], [[1yw8]], [[1yw9]] - hMet-AP+Mn+inhibitor<br />
-
[[2gtx]], [[2gu7]] – EcMet-AP<br />
+
**[[2gtx]], [[2gu7]] – EcMet-AP<br />
-
[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br />
+
**[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br />
-
[[1mat]] – EcMet-AP+Co<br />
+
**[[1mat]] – EcMet-AP+Co<br />
-
[[2mat]], [[4mat]] - EcMet-AP (mutant)+Co<br />
+
**[[2mat]], [[4mat]] - EcMet-AP (mutant)+Co<br />
-
[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br />
+
**[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br />
-
[[2b3h]], [[2b3k]] - hMet-AP+Co<br />
+
**[[2b3h]], [[2b3k]] - hMet-AP+Co<br />
-
[[1boa]] - hMet-AP+Co+ angiogenesis inhibitor<br />
+
**[[1boa]] - hMet-AP+Co+ angiogenesis inhibitor<br />
-
[[2b3l]] – hMet-AP<br />
+
**[[2b3l]] – hMet-AP<br />
-
[[1kq0]], [[1kq9]] – hMet-AP+methionine<br />
+
**[[1kq0]], [[1kq9]] – hMet-AP+methionine<br />
-
[[2gz5]], [[2adu]], [[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[4ikr]], [[4iks]], [[4ikt]], [[4iku]] – hMet-AP+Co+inhibitor<br />
+
**[[2gz5]], [[2adu]], [[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[4ikr]], [[4iks]], [[4ikt]], [[4iku]] – hMet-AP+Co+inhibitor<br />
-
[[1r58]], [[1r5g]], [[1r5h]], [[4fli]], [[4flj]], [[4flk]], [[4fll]] - hMet-AP+Mn+inhibitor<br />
+
**[[1r58]], [[1r5g]], [[1r5h]], [[4fli]], [[4flj]], [[4flk]], [[4fll]] - hMet-AP+Mn+inhibitor<br />
-
[[2g6p]] - hMet-AP truncated+Mn+inhibitor<br />
+
**[[2g6p]] - hMet-AP truncated+Mn+inhibitor<br />
-
[[1qxw]], [[1qxy]], [[1qxz]] – Met-AP+Co+inhibitor - ''Staphylococcus aureus''<br />
+
**[[1qxw]], [[1qxy]], [[1qxz]] – Met-AP+Co+inhibitor - ''Staphylococcus aureus''<br />
-
[[1o0x]] – TmMet-AP<br />
+
**[[1o0x]] – TmMet-AP<br />
-
[[3s6b]] – PfMet-AP + Fe <br />
+
**[[3s6b]] – PfMet-AP + Fe <br />
-
[[4fuk]] – TbMet-AP + Zn – ''Trypanosoma brucei''<br />
+
**[[4fuk]] – TbMet-AP + Zn – ''Trypanosoma brucei''<br />
-
[[4km3]] – SpAP<br />
+
**[[4km3]] – SpAP<br />
-
===Arginine aminopeptidase===
+
*Arginine aminopeptidase
-
[[4jbs]] – hArg-AP+ Zn + inhibitor<br />
+
**[[4jbs]] – hArg-AP+ Zn + inhibitor<br />
-
===Aspartic acid aminopeptidase===
+
*Aspartic acid aminopeptidase
-
[[3l6s]], [[4dyo]] – hAsp-AP+aspartic hydroxamate<br />
+
**[[3l6s]], [[4dyo]] – hAsp-AP+aspartic hydroxamate<br />
-
[[3var]], [[3vat]] – bAsp-AP<br />
+
**[[3var]], [[3vat]] – bAsp-AP<br />
-
[[4eme]] – PfAsp-AP + Zn
+
**[[4eme]] – PfAsp-AP + Zn
-
===Asparagine aminopeptidase===
+
*Asparagine aminopeptidase
-
[[3c17]], [[2zak]] – EcAsn-AP (mutant)<br />
+
**[[3c17]], [[2zak]] – EcAsn-AP (mutant)<br />
-
[[2zal]] – EcAsn-AP+Asp<br />
+
**[[2zal]] – EcAsn-AP+Asp<br />
-
[[2gez]] – Asn-AP – ''Lupinus luteus''
+
**[[2gez]] – Asn-AP – ''Lupinus luteus''
-
===Serine aminopeptidase===
+
*Serine aminopeptidase
-
[[1b65]] – OaSer-AP – ''Ochrobactrum anthropi''
+
**[[1b65]] – OaSer-AP – ''Ochrobactrum anthropi''
-
===Cytosolic aminopeptidase===
+
*Cytosolic aminopeptidase
-
[[3pei]] – Cyt-AP – ''Francisella tularensis''<br />
+
**[[3pei]] – Cyt-AP – ''Francisella tularensis''<br />
-
[[3kzw]] – Cyt-AP – ''Staphylococcus aureus''<br />
+
**[[3kzw]] – Cyt-AP – ''Staphylococcus aureus''<br />
-
[[3ij3]] – Cyt-AP – ''Coxiella burnetii''
+
**[[3ij3]] – Cyt-AP – ''Coxiella burnetii''
-
===Aminopeptidase 2===
+
*Aminopeptidase 2
-
[[3se6]] – hAPN<br />
+
**[[3se6]] – hAPN<br />
-
[[4e36]] – hAPN + Zn
+
**[[4e36]] – hAPN + Zn
-
===Non-specific aminopeptidase===
+
*Non-specific aminopeptidase
-
[[2ek8]] – AnAP – Aneurinibacillus<br />
+
**[[2ek8]] – AnAP – Aneurinibacillus<br />
-
[[2ek9]] – AnAP+bestatin<br />
+
**[[2ek9]] – AnAP+bestatin<br />
-
[[1y0r]], [[1xfo]] – PhAP<br />
+
**[[1y0r]], [[1xfo]] – PhAP<br />
-
[[1y0y]] – PhAP+amastatin<br />
+
**[[1y0y]] – PhAP+amastatin<br />
-
[[1amp]] - VpAP<br />
+
**[[1amp]] - VpAP<br />
-
[[1cp6]], [[1igb]] – VpAP+inhibitor<br />
+
**[[1cp6]], [[1igb]] – VpAP+inhibitor<br />
-
[[1ei5]] – OaAP<br />
+
**[[1ei5]] – OaAP<br />
-
[[3edy]], [[3ee6]] – hTripeptidyl-AP <br />
+
**[[3edy]], [[3ee6]] – hTripeptidyl-AP <br />
-
[[3zn8]] – Dipeptidyl-AP B + signal recognition particle protein + signal recognition particle receptor + RNA – yeast<br />
+
**[[3zn8]] – Dipeptidyl-AP B + signal recognition particle protein + signal recognition particle receptor + RNA – yeast<br />
-
[[4efd]] – TbAP M17 + Mn<br />
+
**[[4efd]] – TbAP M17 + Mn<br />
-
[[4fgm]] – AP N + Zn – ''Idiomarina loihiensis''<br />
+
**[[4fgm]] – AP N + Zn – ''Idiomarina loihiensis''<br />
-
[[4icq]] – SpAP Peps + Zn<br />
+
**[[4icq]] – SpAP Peps + Zn<br />
-
[[4icr]] – SpAP Peps (mutant) + Zn<br />
+
**[[4icr]] – SpAP Peps (mutant) + Zn<br />
-
[[4ics]] – SpAP Peps (mutant) + Zn + Trp + Gly<br />
+
**[[4ics]] – SpAP Peps (mutant) + Zn + Trp + Gly<br />
-
===Cold-activated aminopeptidase===
+
*Cold-activated aminopeptidase
-
[[3cia]] – Col-AP – ''Colwellia psychrerythraea''
+
**[[3cia]] – Col-AP – ''Colwellia psychrerythraea''
-
===Deblocking aminopeptidase===
+
*Deblocking aminopeptidase
-
[[2gre]] – DAP – ''Bacillus cereus''
+
**[[2gre]] – DAP – ''Bacillus cereus''
-
===Heat stable aminopeptidase===
+
*Heat stable aminopeptidase
-
[[2ayi]] – AmpT – ''Thermus thermophilus''
+
**[[2ayi]] – AmpT – ''Thermus thermophilus''
-
===Aminopeptidase from ''Staphylococcus aureus''===
+
*Aminopeptidase from ''Staphylococcus aureus''
-
[[1zjc]] - AmpS
+
**[[1zjc]] - AmpS
-
===Metalloaminopeptidase===
+
*Metalloaminopeptidase
-
[[3q43]], [[3q44]] – PfPFAP (mutant) + bestatin derivative<br />
+
**[[3q43]], [[3q44]] – PfPFAP (mutant) + bestatin derivative<br />
-
===''Stereomyces griesus'' aminopeptidase===
+
*''Stereomyces griesus'' aminopeptidase
-
[[1xjo]], [[1cp7]] - SGAP<br />
+
**[[1xjo]], [[1cp7]] - SGAP<br />
-
[[1qq9]], [[1f2o]], [[1f2p]], [[1tf8]], [[1tf9]], [[1tkf]], [[1tkh]], [[1tkj]], [[1xbu]] - SGAP + amino acid
+
**[[1qq9]], [[1f2o]], [[1f2p]], [[1tf8]], [[1tf9]], [[1tkf]], [[1tkh]], [[1tkj]], [[1xbu]] - SGAP + amino acid
-
===β-peptidyl aminopeptidase===
+
*β-peptidyl aminopeptidase
-
[[3n2w]] – SxBapA – ''Sphingosinicella xenopeptidilytica''<br />
+
**[[3n2w]] – SxBapA – ''Sphingosinicella xenopeptidilytica''<br />
-
[[3n5i]] – SxBapA (mutant)<br />
+
**[[3n5i]] – SxBapA (mutant)<br />
-
[[3n33]] – SxBapA + AEBSF<br />
+
**[[3n33]] – SxBapA + AEBSF<br />
-
[[3ndv]], [[3nfb]] – SxBapA + ampicillin
+
**[[3ndv]], [[3nfb]] – SxBapA + ampicillin
-
===M1 family aminopeptidase===
+
*M1 family aminopeptidase
-
[[4j3b]] – PfAP (mutant)<br />
+
**[[4j3b]] – PfAP (mutant)<br />
-
[[3t8v]] – PfAP M1<br />
+
**[[3t8v]] – PfAP M1<br />
-
[[4k5l]], [[4k5m]], [[4k5n]], [[4k5p]], [[4k5o]] - PfLeu-AP (mutant) + Zn + inhibitor<br />
+
**[[4k5l]], [[4k5m]], [[4k5n]], [[4k5p]], [[4k5o]] - PfLeu-AP (mutant) + Zn + inhibitor<br />
-
===Aminopeptidase C===
+
*Aminopeptidase C
-
[[4k7c]] – AP – ''Lactobacillus rahmnosis''<br />
+
**[[4k7c]] – AP – ''Lactobacillus rahmnosis''<br />
 +
}}
{{Clear}}
{{Clear}}

Revision as of 08:45, 17 November 2014

Bacterial leucine aminopeptidase complex with 8-hydroxyquinoline, glycerol, SCN, Zn+2 (magenta), Na+ (cyan) and Cl- (green) ions (PDB code 3vh9)

Drag the structure with the mouse to rotate

3D Structures of Aminopeptidase

Updated on 17-November-2014

Additional Resources

For additional information, see:
Amino Acid Synthesis & Metabolism
Streptomyces griseus Aminopeptidase (SGAP)

References

  1. ↑ Hanaya K, Suetsugu M, Saijo S, Yamato I, Aoki S. Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn(2+) fluorophores, kinetic, and X-ray crystallographic study. J Biol Inorg Chem. 2012 Feb 5. PMID:22311113 doi:10.1007/s00775-012-0873-4

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