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Fatty acid synthase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===FAS===
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*Fatty acid synthase
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[[1kp9]] – MtFAS CmaA1 – ''Mycobacterium tuberculosis''<br />
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**[[1kp9]] – MtFAS CmaA1 – ''Mycobacterium tuberculosis''<br />
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[[4bjd]], [[4bje]], [[4bjf]], [[4bjg]] – MtFAS I – Cryo-EM<br />
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**[[4bjd]], [[4bje]], [[4bjf]], [[4bjg]] – MtFAS I – Cryo-EM<br />
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[[3zen]], [[4b3y]] – FAS – ''Mycobacterium smegmatis'' – Cryo-EM<br />
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**[[3zen]], [[4b3y]] – FAS – ''Mycobacterium smegmatis'' – Cryo-EM<br />
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[[1xkt]] – hFAS thioesterase domain – human<br />
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**[[1xkt]] – hFAS thioesterase domain – human<br />
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[[2jfd]] – hFAS MAT domain<br />
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**[[2jfd]] – hFAS MAT domain<br />
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[[3hhd]] - hFAS KS-MAT domain<br />
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**[[3hhd]] - hFAS KS-MAT domain<br />
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[[2cf2]], [[2vz8]] – pFAS – pig<br />
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**[[2cf2]], [[2vz8]] – pFAS – pig<br />
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[[2uv8]], [[3hmj]] – yFAS α+β subunits - yeast<br />
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**[[2uv8]], [[3hmj]] – yFAS α+β subunits - yeast<br />
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[[2pff]], [[2was]] – yFAS α subunit<br />
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**[[2pff]], [[2was]] – yFAS α subunit<br />
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[[2uv9]] – TlFAS α subunits – ''Thermomyces lanuginosus''<br />
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**[[2uv9]] – TlFAS α subunits – ''Thermomyces lanuginosus''<br />
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[[2uva]] – TlFAS β subunits<br />
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**[[2uva]] – TlFAS β subunits<br />
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[[2png]] – FAS ACP domain – rat<br />
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**[[2png]] – FAS ACP domain – rat<br />
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[[1t8k]] – EcFAS ACP domain - ''Escherichia coli''<br />
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**[[1t8k]] – EcFAS ACP domain - ''Escherichia coli''<br />
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[[2k92]], [[2k93]], [[2k94]] - EcFAS ACP domain – NMR
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**[[2k92]], [[2k93]], [[2k94]] - EcFAS ACP domain – NMR
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===FAS complex with fatty acid===
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*FAS complex with fatty acid
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[[1kpg]] – MtFAS CmaA1 + cetyl-trimethyl-ammonium + adenosyl homocysteine<br />
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**[[1kpg]] – MtFAS CmaA1 + cetyl-trimethyl-ammonium + adenosyl homocysteine<br />
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[[1kph]] – MtFAS CmaA1 + didecyl-dimethyl-ammonium + adenosyl homocysteine<br />
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**[[1kph]] – MtFAS CmaA1 + didecyl-dimethyl-ammonium + adenosyl homocysteine<br />
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[[1kpi]] – MtFAS CmaA2 + didecyl-dimethyl-ammonium + adenosyl homocysteine<br />
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**[[1kpi]] – MtFAS CmaA2 + didecyl-dimethyl-ammonium + adenosyl homocysteine<br />
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[[3hem]] - MtFAS CmaA1 + dioctylamine<br />
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**[[3hem]] - MtFAS CmaA1 + dioctylamine<br />
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[[3tjm]] – hFAS thioesterase domain + fatty acid<br />
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**[[3tjm]] – hFAS thioesterase domain + fatty acid<br />
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[[2fae]] – EcFAS ACP domain + decanethioate<br />
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**[[2fae]] – EcFAS ACP domain + decanethioate<br />
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[[2fad]] – EcFAS ACP domain + heptanthioate
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**[[2fad]] – EcFAS ACP domain + heptanthioate
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===FAS complex with reactants===
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*FAS complex with reactants
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[[2jfk]] – hFAS + malonyl CoA<br />
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**[[2jfk]] – hFAS + malonyl CoA<br />
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[[2uvc]] – TlFAS β subunits + NADP<BR />
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**[[2uvc]] – TlFAS β subunits + NADP<BR />
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[[2uvb]] – TlFAS α subunits + NADP<BR />
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**[[2uvb]] – TlFAS α subunits + NADP<BR />
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[[2wat]] – yFAS α subunit + CoA<br />
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**[[2wat]] – yFAS α subunit + CoA<br />
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[[2vz9]] – pFAS + NADP<BR />
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**[[2vz9]] – pFAS + NADP<BR />
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===FAS complex with protein===
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*FAS complex with protein
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[[2fhs]] – EcFAS ACP domain + enoyl-ACP reductase <br />
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**[[2fhs]] – EcFAS ACP domain + enoyl-ACP reductase <br />
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[[3ejb]] - EcFAS ACP domain + biotin biosynthesis cytochrome P450-like enzyme<br />
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**[[3ejb]] - EcFAS ACP domain + biotin biosynthesis cytochrome P450-like enzyme<br />
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[[3ejb]], [[3eje]] - EcFAS ACP domain + biotin biosynthesis cytochrome P450-like enzyme + fatty acid<br />
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**[[3ejb]], [[3eje]] - EcFAS ACP domain + biotin biosynthesis cytochrome P450-like enzyme + fatty acid<br />
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[[2cg5]] - hFAS ACP domain + AASD-PPT
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**[[2cg5]] - hFAS ACP domain + AASD-PPT
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===FAS complex with inhibitor===
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*FAS complex with inhibitor
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[[2vkz]] - yFAS α+β subunits + cerulenin<br />
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[[2px6]] – hFAS thioesterase domain + orlistat<br />
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**[[2vkz]] - yFAS α+β subunits + cerulenin<br />
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**[[2px6]] – hFAS thioesterase domain + orlistat<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 13:55, 24 November 2014

Template:STRUCTURE 3tjm

Fatty acid synthase (FAS) catalizes the synthesis of palmitate from acetyl CoA and malonyl CoA into long chain fatty acid. FAS is a multi-domain enzyme. It contains an acyl carrier protein domain (ACP).

3D structures of fatty acid synthase

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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