Neurexin
From Proteopedia
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{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | {{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | ||
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== 3D Structures of Neurexin == | == 3D Structures of Neurexin == | ||
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- | + | {{#tree:id=OrganizedByTopic|openlevels=0| | |
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- | + | *Neurexin | |
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- | + | **[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br /> | |
+ | **[[3bod]], [[3bop]] - mNRXN-1α LNS domain<br /> | ||
+ | **[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br /> | ||
+ | **[[2r16]] - rNRXN-1α LNS domain+Ca<br /> | ||
+ | **[[1c4r]] - rNRXN-1α LNS domain<br /> | ||
+ | **[[3mw4]] - mNRXN-1α LNS domain<br /> | ||
+ | **[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br /> | ||
+ | **[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br /> | ||
+ | **[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br /> | ||
+ | **[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br /> | ||
+ | **[[2r1d]] - rNRXN-1β LNS/LG domain | ||
- | + | *NRXN+Neuroligin | |
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+ | **[[2xb6]], [[2wqz]] – rNRXN-1α LNS domain +hNLGN-4 cholinesterase domain<br /> | ||
+ | **[[3b3q]] - hNRXN-1α LNS domain+mNLGN-4 cholinesterase domain<br /> | ||
+ | **[[3biw]] - rNRXN-1α LNS domain+rNLGN-1 cholinesterase domain<br /> | ||
+ | **[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain | ||
+ | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Revision as of 11:34, 1 December 2014
Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. See Neurodevelopmental Disorders.
For Structural Analysis of Neurexin, See: Neuroligin-Neurexin Interaction
3D Structures of Neurexin
01-December-2014
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Joel L. Sussman, Jaime Prilusky