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Saposin
From Proteopedia
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *Saposin A | |
| - | [[2dob]] – hSapA residues 60-140 – human<br /> | + | **[[2dob]] – hSapA residues 60-140 – human<br /> |
| - | [[4ddj]] – hSapA + LDAO<br /> | + | **[[4ddj]] – hSapA + LDAO<br /> |
| - | + | *Saposin B | |
| - | [[1n69]] – hSapB + lipid | + | **[[1n69]] – hSapB + lipid |
| - | + | *Saposin C | |
| - | [[1m12]], [[1sn6]] – hSapC – NMR<br /> | + | **[[1m12]], [[1sn6]] – hSapC – NMR<br /> |
| - | [[2gtg]], [[2qyp]], [[2z9a]] – hSapC residues 311-391 | + | **[[2gtg]], [[2qyp]], [[2z9a]] – hSapC residues 311-391 |
| - | + | *Saposin D | |
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| - | + | ||
| - | + | ||
| + | **[[3bqp]], [[3bqq]], [[2r1q]], [[2rb3]] - hSapD residues 405-484<br /> | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:21, 10 December 2014
Saposin (Sap) is a small protein which functions as activator of lipid-degrading enzymes. They act by isolating the lipid substrate from the membrane. Sap is synthesized as a precursor – prosaposin – which contain 4 SapB active domains and 2 SapA domains which are cleaved off. For more details see Molecular Playground/Saposin C.
3D Structures of Saposin
Updated on 10-December-2014
