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4j8m

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'''Unreleased structure'''
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==Aurora A in complex with CD532==
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<StructureSection load='4j8m' size='340' side='right' caption='[[4j8m]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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The entry 4j8m is ON HOLD until Sep 10 2015
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4j8m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J8M FirstGlance]. <br>
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Authors: Meyerowitz, J.G., Gustafson, W.C., Shokat, K.M., Weiss, W.A.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJ5:1-[4-[[4-[(5-CYCLOPENTYL-1H-PYRAZOL-3-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA'>CJ5</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
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Description: Aurora A in complex with CD532
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j8n|4j8n]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j8m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j8m RCSB], [http://www.ebi.ac.uk/pdbsum/4j8m PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Gustafson, W C.]]
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[[Category: Meyerowitz, J G.]]
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[[Category: Shokat, K M.]]
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[[Category: Weiss, W A.]]
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[[Category: Aurora some]]
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[[Category: Kinase inhibitor]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Type ii]]

Revision as of 10:06, 10 September 2014

Aurora A in complex with CD532

4j8m, resolution 1.85Å

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