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1dps

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|PDB= 1dps |SIZE=350|CAPTION= <scene name='initialview01'>1dps</scene>, resolution 1.60&Aring;
|PDB= 1dps |SIZE=350|CAPTION= <scene name='initialview01'>1dps</scene>, resolution 1.60&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
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|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
|ACTIVITY=
|ACTIVITY=
|GENE= DPS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
|GENE= DPS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dps OCA], [http://www.ebi.ac.uk/pdbsum/1dps PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dps RCSB]</span>
}}
}}
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[[Category: Hogle, J M.]]
[[Category: Hogle, J M.]]
[[Category: Kolter, R.]]
[[Category: Kolter, R.]]
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[[Category: NA]]
 
[[Category: dna-binding protein]]
[[Category: dna-binding protein]]
[[Category: ferritin]]
[[Category: ferritin]]
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[[Category: stationary phase]]
[[Category: stationary phase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:42:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:46:17 2008''

Revision as of 16:46, 30 March 2008

Image:1dps.jpg


PDB ID 1dps

Drag the structure with the mouse to rotate
, resolution 1.60Å
Ligands:
Gene: DPS (Escherichia coli)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA


Overview

The crystal structure of Dps, a DNA-binding protein from starved E. coli that protects DNA from oxidative damage, has been solved at 1.6 A resolution. The Dps monomer has essentially the same fold as ferritin, which forms a 24-mer with 432 symmetry, a hollow core and pores at the three-fold axes. Dps forms a dodecamer with 23 (tetrahedral) point group symmetry which also has a hollow core and pores at the three-folds. The structure suggests a novel DNA-binding motif and a mechanism for DNA protection based on the sequestration of Fe ions.

About this Structure

1DPS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The crystal structure of Dps, a ferritin homolog that binds and protects DNA., Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM, Nat Struct Biol. 1998 Apr;5(4):294-303. PMID:9546221

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