Transthyretin

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Transthyretin===
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*Transthyretin
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[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]] – hTTR – human<br />
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**[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]] – hTTR – human<br />
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[[3u2j]] – hTTR - neutron<br />
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**[[3u2j]] – hTTR - neutron<br />
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[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant)
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**[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant)
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[[1ttr]] – hTTR (cardiomyapatic mutant)
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**[[1ttr]] – hTTR (cardiomyapatic mutant)
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[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]] – hTTR (mutant)
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**[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]] – hTTR (mutant)
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[[1tfp]] – TTR – chicken
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**[[1tfp]] – TTR – chicken
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[[2qpf]] – TTR - mouse
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**[[2qpf]] – TTR - mouse
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[[1oo2]], [[1sn2]] – gsTTR – gilthead seabream
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**[[1oo2]], [[1sn2]] – gsTTR – gilthead seabream
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[[1gke]] – rTTR – rat
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**[[1gke]] – rTTR – rat
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===TTR binary complexes===
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*Transthyretin binary complexes
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[[1thc]], [[2h1x]], [[2h6u]] – hTTR + hydroxyaurone derivative
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**[[1thc]], [[2h1x]], [[2h6u]] – hTTR + hydroxyaurone derivative
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[[1tlm]] – hTTR + milrinone
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**[[1tlm]] – hTTR + milrinone
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[[1bm7]], [[3ozl]] – hTTR + flufenamic acid
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**[[1bm7]], [[3ozl]] – hTTR + flufenamic acid
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[[1dvs]], [[1dvt]], [[1dvu]], [[1dvx]], [[1dvy]], [[1dvz]], [[1tt6]], [[1tz8]], [[2f8i]], [[2fbr]], [[2flm]], [[2g5u]], [[2g9k]], [[2gab]], [[2qgc]], [[2qgd]], [[2qge]], [[3cn0]], [[3cn1]], [[3cn2]], [[3cn3]], [[3cn4]], [[3esn]], [[3eso]], [[3esp]], [[3glz]], [[3gs0]], [[3gs4]], [[3gs7]], [[3imr]], [[3ims]], [[3imt]], [[3imu]], [[3imv]], [[3imw]], [[3ipb]], [[3ipe]], [[3m10]], [[2fbr]], [[2flm]], [[3m1o]], [[3tct]], [[4fi7]], [[4fi8]], [[4fi6]] – hTTR + amyloid disease inhibitor<br />
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**[[1dvs]], [[1dvt]], [[1dvu]], [[1dvx]], [[1dvy]], [[1dvz]], [[1tt6]], [[1tz8]], [[2f8i]], [[2fbr]], [[2flm]], [[2g5u]], [[2g9k]], [[2gab]], [[2qgc]], [[2qgd]], [[2qge]], [[3cn0]], [[3cn1]], [[3cn2]], [[3cn3]], [[3cn4]], [[3esn]], [[3eso]], [[3esp]], [[3glz]], [[3gs0]], [[3gs4]], [[3gs7]], [[3imr]], [[3ims]], [[3imt]], [[3imu]], [[3imv]], [[3imw]], [[3ipb]], [[3ipe]], [[3m10]], [[2fbr]], [[2flm]], [[3m1o]], [[3tct]], [[4fi7]], [[4fi8]], [[4fi6]] – hTTR + amyloid disease inhibitor<br />
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[[4his]], [[4hiq]] - hTTR (mutant) + amyloid disease inhibitor<br />
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**[[4his]], [[4hiq]] - hTTR (mutant) + amyloid disease inhibitor<br />
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[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br />
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**[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br />
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[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br />
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**[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br />
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[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]] – hTTR + inhibitor
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**[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]] – hTTR + inhibitor
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[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]] – hTTR + phenol derivative<br />
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**[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]] – hTTR + phenol derivative<br />
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[[4l1s]] - hTTR + benzamide derivative<br />
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**[[4l1s]] - hTTR + benzamide derivative<br />
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[[4l1t]] - hTTR + benzoate derivative<br />
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**[[4l1t]] - hTTR + benzoate derivative<br />
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[[4n85]], [[4n86]] - hTTR + glabridin<br />
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**[[4n85]], [[4n86]] - hTTR + glabridin<br />
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[[4n87]] - hTTR (mutant) + glabridin<br />
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**[[4n87]] - hTTR (mutant) + glabridin<br />
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[[2b14]], [[2b16]] – hTTR (mutant) + phenol derivative
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**[[2b14]], [[2b16]] – hTTR (mutant) + phenol derivative
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[[3kgt]], [[3kgu]] – hTTR (mutant) + genistein
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**[[3kgt]], [[3kgu]] – hTTR (mutant) + genistein
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[[3ng5]] – hTTR (mutant) + epigallocatechin gallate
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**[[3ng5]] – hTTR (mutant) + epigallocatechin gallate
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[[3nes]], [[3nex]] – hTTR (mutant) + inhibitor
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**[[3nes]], [[3nex]] – hTTR (mutant) + inhibitor
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[[1tyr]] – hTTR + retinoic acid
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**[[1tyr]] – hTTR + retinoic acid
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[[1kgi]] – rTTR + tetraiodotyroacetic acid
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**[[1kgi]] – rTTR + tetraiodotyroacetic acid
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[[1z7j]] - hTTR + tetraiodotyroacetic acid
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**[[1z7j]] - hTTR + tetraiodotyroacetic acid
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[[1kgj]] – rTTR + dibromoflavone
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**[[1kgj]] – rTTR + dibromoflavone
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[[1zcr]], [[1zd6]] – hTTR + anion<br />
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**[[1zcr]], [[1zd6]] – hTTR + anion<br />
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[[3ssg]] – hTTR + Zn<br />
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**[[3ssg]] – hTTR + Zn<br />
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[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]] – hTTR + anti-inflammatory drug<br />
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**[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]] – hTTR + anti-inflammatory drug<br />
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[[4i89]] - hTTR (mutant) + anti-inflammatory drug <br />
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**[[4i89]] - hTTR (mutant) + anti-inflammatory drug <br />
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[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br />
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**[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br />
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[[3b56]] – hTTR + salicylic acid derivative<br />
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**[[3b56]] – hTTR + salicylic acid derivative<br />
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[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br />
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**[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br />
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===TTR complexes with retinol-binding protein===
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*Transthyretin complexes with retinol-binding protein
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[[1rlb]], [[1qab]] – hTTR + RBP
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**[[1rlb]], [[1qab]] – hTTR + RBP
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[[2wqa]] – hTTR + RBP + oleic acid
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**[[2wqa]] – hTTR + RBP + oleic acid
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[[3bsz]] – hTTR + RBP + antibody
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**[[3bsz]] – hTTR + RBP + antibody
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===TTR complexes with thyroxine===
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*Transthyretin complexes with thyroxine
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[[2rox]], [[1ict]] – hTTR + T4
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**[[2rox]], [[1ict]] – hTTR + T4
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[[3ozk]] – hTTR (mutant) + T4
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**[[3ozk]] – hTTR (mutant) + T4
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[[1tha]], [[2roy]] – hTTR + T4 derivative
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**[[1tha]], [[2roy]] – hTTR + T4 derivative
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[[1ie4]] – rTTR + T4
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**[[1ie4]] – rTTR + T4
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[[1sn0]] – gsTTR + T4
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**[[1sn0]] – gsTTR + T4
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[[1sn5]] – gsTTR + T4 derivative
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**[[1sn5]] – gsTTR + T4 derivative
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:14, 15 December 2014

Template:STRUCTURE 1rlb
 

Transthyretin (TTR) is a serum carrier of the thyroid hormone thyroxine (T4) and retinol through its association with retinol-binding protein (RBP). Many small molecules bind to TTR T4-binding site. TTR is known to be associated with amyloid diseases.

3D structures of transthyretin

Updated on 15-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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