Uridine 5'-monophosphate synthase

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==3D structures of uridine 5'-monophosphate synthase==
==3D structures of uridine 5'-monophosphate synthase==
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===Uridine 5’-monophosphate synthase OPD subunit===
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[3gdk]] - yOPD – yeast<br />
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*Uridine 5’-monophosphate synthase OPD subunit
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[[1dqw]], [[3gdr]], [[3gdm]] – yOPD (mutant) <br />
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[[2eaw]], [[2jgy]], [[2p1f]], [[2qcc]], [[2qce]] - hOPD – human
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===Uridine 5’-monophosphate synthase OPD subunit complex===
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**[[3gdk]] - yOPD – yeast<br />
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**[[1dqw]], [[3gdr]], [[3gdm]] – yOPD (mutant) <br />
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**[[2eaw]], [[2jgy]], [[2p1f]], [[2qcc]], [[2qce]] - hOPD – human
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[[2v30]], [[2qcd]] - hOPD + UMP<br />
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*Uridine 5’-monophosphate synthase OPD subunit complex
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[[3ewy]] - hOPD (mutant) + UMP<br />
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[[3gdl]] - yOPD + UMP derivative<br />
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[[1dqx]], [[3gdt]] - yOPD (mutant) + UMP derivative<br />
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[[2qcg]], [[2qch]], [[3bgg]], [[3bgj]], [[3bk0]], [[3g3d]], [[3g3m]], [[3ewz]], [[3ex2]], [[3ex3]], [[3ex4]], [[3dbp]], [[3l0k]], [[3l0n]], [[3mo7]], [[3mw7]] - hOPD + UMP derivative<br />
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[[3bvj]] - hOPD + xanthosine 5’-monophosphate<br />
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[[2qcf]], [[2qcm]], [[2qcn]], [[3ewu]], [[3ewx]], [[3ex6]] - hOPD (mutant) + UMP derivative<br />
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[[3mi2]], [[4hib]], [[4hkp]] - hOPD + inhibitor<br />
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[[3ex1]] - hOPD + UMP derivative + UMP<br />
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[[2qcl]] - yOPD (mutant) + OMP
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===Uridine 5’-monophosphate synthase OPRT subunit complex===
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**[[2v30]], [[2qcd]] - hOPD + UMP<br />
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**[[3ewy]] - hOPD (mutant) + UMP<br />
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**[[3gdl]] - yOPD + UMP derivative<br />
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**[[1dqx]], [[3gdt]] - yOPD (mutant) + UMP derivative<br />
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**[[2qcg]], [[2qch]], [[3bgg]], [[3bgj]], [[3bk0]], [[3g3d]], [[3g3m]], [[3ewz]], [[3ex2]], [[3ex3]], [[3ex4]], [[3dbp]], [[3l0k]], [[3l0n]], [[3mo7]], [[3mw7]] - hOPD + UMP derivative<br />
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**[[3bvj]] - hOPD + xanthosine 5’-monophosphate<br />
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**[[2qcf]], [[2qcm]], [[2qcn]], [[3ewu]], [[3ewx]], [[3ex6]] - hOPD (mutant) + UMP derivative<br />
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**[[3mi2]], [[4hib]], [[4hkp]] - hOPD + inhibitor<br />
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**[[3ex1]] - hOPD + UMP derivative + UMP<br />
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**[[2qcl]] - yOPD (mutant) + OMP
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[[2wns]] - hOPRT + OMP
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*Uridine 5’-monophosphate synthase OPRT subunit complex
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**[[2wns]] - hOPRT + OMP
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:32, 17 December 2014

Template:STRUCTURE 2v30

Uridine 5’-monophosphate synthase (UMPS) is a bifunctional enzyme catalyzes the formation of uridine monophosphate (UMP). UMPS N-terminal domain is an orotate phosphoribosyl transferase (OPRT) subunit which catalyzes the addition of ribose-phosphate to orotate forming orotidine 5’-monophosphate (OMP). The C-terminal subunit is orotidine 5’-phosphate decarboxylase (OPD) which decarboxylates OMP to form UMP.

3D structures of uridine 5'-monophosphate synthase

Updated on 17-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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