Laccase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===CotA laccase===
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*CotA laccase
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[[2x87]], [[2x88]], [[1w6l]], [[1w6w]], [[1w8e]], [[1gsk]] – BsCotAl – ''Bacillus subtilis''<br />
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**[[2x87]], [[2x88]], [[1w6l]], [[1w6w]], [[1w8e]], [[1gsk]] – BsCotAl – ''Bacillus subtilis''<br />
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[[2bhf]] - BsCotAl reduced<br />
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**[[2bhf]] - BsCotAl reduced<br />
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[[2wsd]], [[4ako]], [[4akp]], [[4akq]] – BsCotAl (mutant)<br />
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**[[2wsd]], [[4ako]], [[4akp]], [[4akq]] – BsCotAl (mutant)<br />
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[[1of0]], [[3zdw]] - BsCotAl + EBS<br />
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**[[1of0]], [[3zdw]] - BsCotAl + EBS<br />
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[[4a66]], [[4a67]], [[4a68]] - BsSCP (mutant) + Cu + peroxide<br />
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**[[4a66]], [[4a67]], [[4a68]] - BsSCP (mutant) + Cu + peroxide<br />
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[[1uvw]] - BsCotAl + ABTS
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**[[1uvw]] - BsCotAl + ABTS
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===CotS laccase===
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*CotS laccase
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[[1nps]] – CotSl N terminal – ''Myxococcus xanthus''
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**[[1nps]] – CotSl N terminal – ''Myxococcus xanthus''
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===CueO laccase===
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*CueO laccase
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}}
See [[Blue copper oxidase CueO]]
See [[Blue copper oxidase CueO]]
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:28, 20 November 2014

CotA laccase complex with glycerol, O2 and Cu+2 (orange), 1w6l

Drag the structure with the mouse to rotate

CotA laccase belong to the multi-copper oxidase family. The multi-copper oxidases constitute a family of enzymes whose principal members are laccase (benzenediol oxygen oxidoreductase, EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA 1w6l comprises three cupredoxin domain and four copper ions organised in : a and


The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically coupled through an hydroxyl moiety in between them, and one type 2 copper ion.‡ The mononuclear copper is able to accept an electron froma variety of phenolic substrates and then transmits it to the trinuclear centre.

3D structures of CotA laccase

Updated on 20-November-2014

See Blue copper oxidase CueO

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