NK cell receptor

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{{#tree:id=OrganizedByTopic|openlevels=0|
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==Activating NK cell receptors==
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*'''Activating NK cell receptors'''
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===NKG2D===
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*NKG2D
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[[1hq8]] – mNKG2D extracellular domain – mouse<br />
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**[[1hq8]] – mNKG2D extracellular domain – mouse<br />
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[[1mpu]] – hNKG2D extracellular domain – human<br />
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**[[1mpu]] – hNKG2D extracellular domain – human<br />
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[[1hyr]] – hNKG2D extracellular domain + class I MHC-like ligand MICA <br />
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**[[1hyr]] – hNKG2D extracellular domain + class I MHC-like ligand MICA <br />
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[[1kcg]] – hNKG2D extracellular domain + class I MHC-like ligand ULBP3<br />
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**[[1kcg]] – hNKG2D extracellular domain + class I MHC-like ligand ULBP3<br />
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[[4pp8]] – mNKG2D extracellular domain + retinoic acid early-inducible protein 1β<br />
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**[[4pp8]] – mNKG2D extracellular domain + retinoic acid early-inducible protein 1β<br />
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[[4pdc]] – hNKG2D extracellular domain + cowpox virus protein<br />
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**[[4pdc]] – hNKG2D extracellular domain + cowpox virus protein<br />
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[[3bdw]] – hNKG2D extracellular domain + CD94<br />
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**[[3bdw]] – hNKG2D extracellular domain + CD94<br />
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[[3bdw]], [[3cii]] – hNKG2D extracellular domain + CD94 + MHC class I antigen E + β-2-microglobulin + HLA G antigen<br />
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**[[3bdw]], [[3cii]] – hNKG2D extracellular domain + CD94 + MHC class I antigen E + β-2-microglobulin + HLA G antigen<br />
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===NKP===
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*NKP
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[[1hkf]] – hNKP44 IG domain <br />
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**[[1hkf]] – hNKP44 IG domain <br />
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[[1oll]], [[1p6f]] – hNKP46 extracellular domain <br />
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**[[1oll]], [[1p6f]] – hNKP46 extracellular domain <br />
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===2B4===
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*2B4
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[[1z2k]] – h2B4 D1 domain - NMR<br />
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**[[1z2k]] – h2B4 D1 domain - NMR<br />
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[[2ptu]] – m2B4 D1 domain <br />
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**[[2ptu]] – m2B4 D1 domain <br />
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[[2ptt]] – h2B4 D1 domain + CD48 antigen<br />
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**[[2ptt]] – h2B4 D1 domain + CD48 antigen<br />
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===Ly49===
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*Ly49
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[[3g8l]], [[3g8k]] – mLy49 C-type lectin-like domain <br />
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**[[3g8l]], [[3g8k]] – mLy49 C-type lectin-like domain <br />
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===CD94===
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*CD94 See [[CD94]]
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See [[CD94]]
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*'''Inhibitory NK cell receptors'''
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==Inhibitory NK cell receptors==
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*KIR
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===KIR===
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[[3vh8]] – hKIR extracellular domain + MHC class I antigen B + β-2-microglobulin + IG κ chain C region<br />
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[[3wuw]] – hKIR extracellular domain + MHC class I antigen B + β-2-microglobulin + peptide<br />
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**[[3vh8]] – hKIR extracellular domain + MHC class I antigen B + β-2-microglobulin + IG κ chain C region<br />
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**[[3wuw]] – hKIR extracellular domain + MHC class I antigen B + β-2-microglobulin + peptide<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:31, 1 December 2014

Template:STRUCTURE 1kcg


Natural killer (NK) cell receptors are located on the innate immune system NK cells. The receptors are differentiated into activating and inhibitory ones. The receptors induce apoptosis upon binding ligands which indicate infection.

3D structures of NK cell receptor

Updated on 01-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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