Farnesyl diphosphate synthase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[1fps]]– cFPS – chicken<br />
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*Farnesyl diphosphate synthase
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[[1ubv]] – cFPS (mutant) <br />
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[[1zw5]], [[2f7m]] – hFPS – human<br />
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[[1rtr]]– FPS – ''Staphylococcus aureus''<br />
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[[1yhk]] – TcFPS – ''Trypanosoma cruzi''<br />
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[[3lvs]], [[3m0g]] – FPS – ''Rhodobacter capsulatus''<br />
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[[3m9u]] – LbFPS – ''Lactobacillus brevis''<br />
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===FPS binary complexes===
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**[[1fps]]– cFPS – chicken<br />
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**[[1ubv]] – cFPS (mutant) <br />
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**[[1zw5]], [[2f7m]] – hFPS – human<br />
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**[[1rtr]]– FPS – ''Staphylococcus aureus''<br />
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**[[1yhk]] – TcFPS – ''Trypanosoma cruzi''<br />
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**[[3lvs]], [[3m0g]] – FPS – ''Rhodobacter capsulatus''<br />
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**[[3m9u]] – LbFPS – ''Lactobacillus brevis''<br />
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[[1yq7]], [[1yv5]], [[2f89]], [[2f8c]], [[2f92]], [[2f94]], [[2f9k]], [[2rah]], [[2opn]], [[2vf6]], [[3b7l]], [[2opm]], [[3n1v]], [[3n1w]], [[3n3l]], [[3n45]], [[3n46]], [[3n49]], [[3n5j]], [[3n6k]], [[3n5h]], [[4dem]], [[4ga3]], [[4jvj]] - hFPS + inhibitor<br />
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*FPS binary complexes
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[[2qis]], [[3cp6]], [[3rye]], [[3s4j]] - hFPS (mutant) + inhibitor<br />
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[[2i19]], [[2ewg]], [[2ogd]], [[2p1c]], [[3dyg]], [[3dyh]], [[3efq]], [[3egt]] - TbFPS + inhibitor – ''Trypanosoma brucei''<br />
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[[1ubw]], [[1ubx]] - cFPS (mutant) + GDP<br />
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[[1uby]] - cFPS (mutant) + dimethylallyl diphosphate<br />
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[[2for]]– FPS + IPP – ''Shigella flexneri''<br />
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[[3id0]]– TcFPS + inhibitor<br />
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[[3pde]] – LbFPS + IPP<br />
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===FPS ternary complexes===
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**[[1yq7]], [[1yv5]], [[2f89]], [[2f8c]], [[2f92]], [[2f94]], [[2f9k]], [[2rah]], [[2opn]], [[2vf6]], [[3b7l]], [[2opm]], [[3n1v]], [[3n1w]], [[3n3l]], [[3n45]], [[3n46]], [[3n49]], [[3n5j]], [[3n6k]], [[3n5h]], [[4dem]], [[4ga3]], [[4jvj]] - hFPS + inhibitor<br />
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**[[2qis]], [[3cp6]], [[3rye]], [[3s4j]] - hFPS (mutant) + inhibitor<br />
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**[[2i19]], [[2ewg]], [[2ogd]], [[2p1c]], [[3dyg]], [[3dyh]], [[3efq]], [[3egt]] - TbFPS + inhibitor – ''Trypanosoma brucei''<br />
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**[[1ubw]], [[1ubx]] - cFPS (mutant) + GDP<br />
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**[[1uby]] - cFPS (mutant) + dimethylallyl diphosphate<br />
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**[[2for]]– FPS + IPP – ''Shigella flexneri''<br />
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**[[3id0]]– TcFPS + inhibitor<br />
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**[[3pde]] – LbFPS + IPP<br />
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[[2f8z]], [[4h5e]] - hFPS + IPP + inhibitor<br />
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*FPS ternary complexes
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[[4h5c]], [[4h3c]], [[4h5d]] - hFPS + phosphate + inhibitor<br />
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[[1rqi]] – EcFPS + IPP + dimethylallyl S-thiolodiphosphate – ''Escherichia coli''<br />
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[[1rqj]] - EcFPS + IPP + inhibitor<br />
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[[1yhl]] – TcFPS + dimethylallyl diphosphate + inhibitor<br />
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[[1yhm]], [[3iba]], [[3ick]], [[3icm]], [[3icn]], [[3icz]], [[4dwb]], [[4dwg]], [[4dxj]], [[4dzw]], [[4e1e]] - TcFPS + IPP + inhibitor<br />
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[[3ez3]] - PvFPS + IPP + inhibitor – ''Plasmodium vivax''<br />
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[[3dyf]] - TbFPS + IPP + inhibitor<br />
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**[[2f8z]], [[4h5e]] - hFPS + IPP + inhibitor<br />
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**[[4h5c]], [[4h3c]], [[4h5d]] - hFPS + phosphate + inhibitor<br />
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**[[1rqi]] – EcFPS + IPP + dimethylallyl S-thiolodiphosphate – ''Escherichia coli''<br />
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**[[1rqj]] - EcFPS + IPP + inhibitor<br />
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**[[1yhl]] – TcFPS + dimethylallyl diphosphate + inhibitor<br />
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**[[1yhm]], [[3iba]], [[3ick]], [[3icm]], [[3icn]], [[3icz]], [[4dwb]], [[4dwg]], [[4dxj]], [[4dzw]], [[4e1e]] - TcFPS + IPP + inhibitor<br />
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**[[3ez3]] - PvFPS + IPP + inhibitor – ''Plasmodium vivax''<br />
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**[[3dyf]] - TbFPS + IPP + inhibitor<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 13:44, 24 November 2014

Template:STRUCTURE 2opm

Farnesyl diphosphate synthase (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate.

3D structures of farnesyl diphosphate synthase

Updated on 24-November-2014

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