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4muj

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4muj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MUJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4muj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MUJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DU:{2-[(BENZYLSULFONYL)CARBAMOYL]-5-METHOXY-1H-INDOL-1-YL}ACETIC+ACID'>2DU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DU:{2-[(BENZYLSULFONYL)CARBAMOYL]-5-METHOXY-1H-INDOL-1-YL}ACETIC+ACID'>2DU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mq6|4mq6]], [[4mue|4mue]], [[4muf|4muf]], [[4mug|4mug]], [[4muh|4muh]], [[4mui|4mui]], [[4mul|4mul]], [[4mun|4mun]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mq6|4mq6]], [[4mue|4mue]], [[4muf|4muf]], [[4mug|4mug]], [[4muh|4muh]], [[4mui|4mui]], [[4mul|4mul]], [[4mun|4mun]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4muj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4muj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4muj RCSB], [http://www.ebi.ac.uk/pdbsum/4muj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4muj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4muj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4muj RCSB], [http://www.ebi.ac.uk/pdbsum/4muj PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell, T L]]
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[[Category: Silvestre, H L.]]
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[[Category: Silvestre, H L]]
[[Category: Atp binding]]
[[Category: Atp binding]]
[[Category: Ligase-ligase inhibitor complex]]
[[Category: Ligase-ligase inhibitor complex]]
[[Category: Pantoate-ligase]]
[[Category: Pantoate-ligase]]

Revision as of 06:13, 25 December 2014

Crystal structure of pantothenate synthetase in complex with 2-(2-(benzylsulfonylcarbamoyl)-5-methoxy-1H-indol-1-yl)acetic acid

4muj, resolution 1.92Å

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