Gramicidin
From Proteopedia
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<Structure load='2xds' size='400' scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/> | <Structure load='2xds' size='400' scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/> | ||
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''.<br /> | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''.<br /> | ||
| - | * '''GCDN S''' is | + | * '''GCDN S''' is an antibiotic cyclic polypeptide.<br /> |
* '''GCDN D''' is a mixture of GCDN A, B, C. <br /> | * '''GCDN D''' is a mixture of GCDN A, B, C. <br /> | ||
| - | + | See theoretical model of [[Gramicidin Channel in Lipid Bilayer]]. | |
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== 3D Structures of Gramicidin == | == 3D Structures of Gramicidin == | ||
Revision as of 09:40, 27 August 2014
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Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis.
- GCDN S is an antibiotic cyclic polypeptide.
- GCDN D is a mixture of GCDN A, B, C.
See theoretical model of Gramicidin Channel in Lipid Bilayer.
Contents |
3D Structures of Gramicidin
Updated on 27-August-2014
Gramicidin A
1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS
Gramicidin D
2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
3lml, 2izq, 3i8i, 3l8l - GCDN D + iodide
1c4d - GCDN D + CsCl
3zq8 – GCDN D + monovaccenin
Gramicidin S
1tk2 – GCDN S + subtilisin savinase – Bacillus lentus
