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Interleukin receptor
From Proteopedia
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | '''Interleukin receptor type I''' | |
| - | + | *Interleukin-2 receptor | |
| - | [[1z92]] – hIL2R α subunit + interleukin-2<br /> | + | **[[1z92]] – hIL2R α subunit + interleukin-2<br /> |
| - | [[2b5i]] - hIL2R α+β+γ subunits + interleukin-2<br /> | + | **[[2b5i]] - hIL2R α+β+γ subunits + interleukin-2<br /> |
| - | [[3qaz]] - hIL2R β+γ subunits + interleukin-2<br /> | + | **[[3qaz]] - hIL2R β+γ subunits + interleukin-2<br /> |
| - | [[2erj]] - hIL2R α (mutant)+β+γ (mutant) subunits + interleukin-2 (mutant)<br /> | + | **[[2erj]] - hIL2R α (mutant)+β+γ (mutant) subunits + interleukin-2 (mutant)<br /> |
| - | [[3qb7]] - hIL2R γ (mutant) subunit + interleukin-2<br /> | + | **[[3qb7]] - hIL2R γ (mutant) subunit + interleukin-2<br /> |
| - | [[3iu3]], [[3nfp]] - hIL2R α subunit + antibody | + | **[[3iu3]], [[3nfp]] - hIL2R α subunit + antibody |
| - | + | *Interleukin-4 receptor | |
| - | [[1iar]] - hIL4R α (mutant) subunit + interleukin-4<br /> | + | **[[1iar]] - hIL4R α (mutant) subunit + interleukin-4<br /> |
| - | [[3bpl]] - hIL4R α + γ subunits + interleukin-4<br /> | + | **[[3bpl]] - hIL4R α + γ subunits + interleukin-4<br /> |
| - | [[3bpn]] - hIL4R α subunit + hIL13R α subunit + interleukin-4<br /> | + | **[[3bpn]] - hIL4R α subunit + hIL13R α subunit + interleukin-4<br /> |
| - | [[3bpo]] - hIL4R α subunit + hIL13R α subunit + interleukin-13 | + | **[[3bpo]] - hIL4R α subunit + hIL13R α subunit + interleukin-13 |
| - | + | *Interleukin-5 receptor | |
| - | [[3qt2]] – hIL5R α (mutant) subunit + interleukin-5<br /> | + | **[[3qt2]] – hIL5R α (mutant) subunit + interleukin-5<br /> |
| - | [[3va2]] - hIL5R α subunit + interleukin-5<br /> | + | **[[3va2]] - hIL5R α subunit + interleukin-5<br /> |
| - | + | *Interleukin-6 receptor or gp130 | |
| - | [[1i1r]] – hIL6R β subunit + interleukin-6 homolog<br /> | + | **[[1i1r]] – hIL6R β subunit + interleukin-6 homolog<br /> |
| - | [[1pvh]] - hIL6R β subunit + leukemia inhILbitory factor<br /> | + | **[[1pvh]] - hIL6R β subunit + leukemia inhILbitory factor<br /> |
| - | [[2hmh]] - mI6R β subunit + suppressor of cytokine signaling 3 – mouse<br /> | + | **[[2hmh]] - mI6R β subunit + suppressor of cytokine signaling 3 – mouse<br /> |
| - | [[4gl9]] - mI6R β subunit + suppressor of cytokine signaling 3 + tyrosine-protein kinase<br /> | + | **[[4gl9]] - mI6R β subunit + suppressor of cytokine signaling 3 + tyrosine-protein kinase<br /> |
| - | [[3l5i]], [[3l5j]], [[3l5h]] - hIL6R β subunit<br /> | + | **[[3l5i]], [[3l5j]], [[3l5h]] - hIL6R β subunit<br /> |
| - | [[1n26]] - hIL6R α subunit<br /> | + | **[[1n26]] - hIL6R α subunit<br /> |
| - | [[2arw]] - hIL6R α subunit - NMR<br /> | + | **[[2arw]] - hIL6R α subunit - NMR<br /> |
| - | [[1p9m]] - hIL6R α + β subunits + interleukin-6 | + | **[[1p9m]] - hIL6R α + β subunits + interleukin-6 |
| - | + | *Interleukin-7 receptor | |
| - | [[3up1]] - hIL7R α subunit<br /> | + | **[[3up1]] - hIL7R α subunit<br /> |
| - | [[3di2]], [[3di3]] – hIL7R α (mutant) subunit + interleukin-7 (mutant) | + | **[[3di2]], [[3di3]] – hIL7R α (mutant) subunit + interleukin-7 (mutant) |
| - | + | *Interleukin-13 receptor | |
| - | [[3lb6]] - hIL13R α2 (mutant) subunit + interleukin-13<br /> | + | **[[3lb6]] - hIL13R α2 (mutant) subunit + interleukin-13<br /> |
| - | [[4hwb]] - hIL13R α1 subunit + antibody<br /> | + | **[[4hwb]] - hIL13R α1 subunit + antibody<br /> |
| - | + | *Interleukin-15 receptor | |
| - | [[2ers]] - hIL15R α subunit sushIL domain – NMR<br /> | + | **[[2ers]] - hIL15R α subunit sushIL domain – NMR<br /> |
| - | [[2z3q]], [[2z3r]], [[2psm]] - hIL15R α subunit + interleukin-15<br /> | + | **[[2z3q]], [[2z3r]], [[2psm]] - hIL15R α subunit + interleukin-15<br /> |
| - | [[4gs7]] - hIL15R α subunit + interleukin-15 + hIL2R β,γ subunits<br /> | + | **[[4gs7]] - hIL15R α subunit + interleukin-15 + hIL2R β,γ subunits<br /> |
| - | + | *Interleukin-17 receptor | |
| - | [[3jvf]] - hIL17RA extracellular domain + interleukin-17F<br /> | + | **[[3jvf]] - hIL17RA extracellular domain + interleukin-17F<br /> |
| - | [[4hsa]] - hIL17RA (mutant) + interleukin-17A<br /> | + | **[[4hsa]] - hIL17RA (mutant) + interleukin-17A<br /> |
| - | [[3vbc]] – mIL17RB<br /> | + | **[[3vbc]] – mIL17RB<br /> |
| - | + | *Interleukin-21 receptor | |
| - | [[3tgx]] – hIL21R extracellular domain (mutant) + interleukin-21 | + | **[[3tgx]] – hIL21R extracellular domain (mutant) + interleukin-21 |
| - | + | '''Interleukin receptor type II''' | |
| - | + | *Interleukin-10 receptor | |
| - | [[1j7v]] – hIL10R α (mutant) subunit + interleukin-10<br /> | + | **[[1j7v]] – hIL10R α (mutant) subunit + interleukin-10<br /> |
| - | [[1lqs]], [[1y6m]], [[1y6n]] - hIL10R α (mutant) subunit + interleukin-10 homolog<br /> | + | **[[1lqs]], [[1y6m]], [[1y6n]] - hIL10R α (mutant) subunit + interleukin-10 homolog<br /> |
| - | [[1y6k ]]- hIL10R α (mutant) subunit + interleukin-10<br /> | + | **[[1y6k ]]- hIL10R α (mutant) subunit + interleukin-10<br /> |
| - | [[3lqm]] - hIL10R β (mutant) subunit | + | **[[3lqm]] - hIL10R β (mutant) subunit |
| - | + | *Interleukin-20 receptor | |
| - | [[4doh]] - hIL20R α,β subunit + interleukin-20<br /> | + | **[[4doh]] - hIL20R α,β subunit + interleukin-20<br /> |
| - | + | *Interleukin-22 receptor | |
| - | [[3g9v]] - hIL22R α subunit + interleukin-22<br /> | + | **[[3g9v]] - hIL22R α subunit + interleukin-22<br /> |
| - | [[3dgc]] – hIL22R α (mutant) subunit + interleukin-22<br /> | + | **[[3dgc]] – hIL22R α (mutant) subunit + interleukin-22<br /> |
| - | [[3dlq]] - hIL22R α (mutant) subunit + interleukin-2 (mutant) | + | **[[3dlq]] - hIL22R α (mutant) subunit + interleukin-2 (mutant) |
| - | + | *Interleukin-28 receptor | |
| - | [[3og4]], [[3og6]] - hIL28R α subunit + interleukin-29<br /> | + | **[[3og4]], [[3og6]] - hIL28R α subunit + interleukin-29<br /> |
| - | + | '''Interleukin receptor of immunoglobulin family''' | |
| - | + | *Interleukin-1 receptor (CD121a, CD121b) | |
| - | [[1itb]] – hI1R1 extracellular domain + interleukin-1 β – human<br /> | + | **[[1itb]] – hI1R1 extracellular domain + interleukin-1 β – human<br /> |
| - | [[1ira]]- hI1R1 extracellular domain + I1R1A<br /> | + | **[[1ira]]- hI1R1 extracellular domain + I1R1A<br /> |
| - | [[1g0y]] - hI1R1 extracellular domain + I1R1A peptide<br /> | + | **[[1g0y]] - hI1R1 extracellular domain + I1R1A peptide<br /> |
| - | [[3o4o]] - hI1R2 + interleukin-1 β<br /> | + | **[[3o4o]] - hI1R2 + interleukin-1 β<br /> |
| - | [[4dep]] – hIL1R1 extracellular domain + interleukin-1 β + + interleukin-1 accessory protein<br /> | + | **[[4dep]] – hIL1R1 extracellular domain + interleukin-1 β + + interleukin-1 accessory protein<br /> |
| - | [[4gaf]] – hIL1R1 extracellular domain + IL1β/IL1RA <br /> | + | **[[4gaf]] – hIL1R1 extracellular domain + IL1β/IL1RA <br /> |
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:32, 30 November 2014
Template:STRUCTURE 2b5i Interleukin receptors (ILR) are cytokine receptor which are classified into type I, type II and . ILR type I are cell surface receptors which recognize cytokines with four α-helical strands. ILR type II are similar to type I but lack the former’s signature sequence: WXSWS. Interleukin-1 receptor belongs to the ILR of immunoglobulin family. IL1R contains two types. Type I (IL1R1) binds interleukin-1 transmitting its inflammatory effect. Interleukin-1 receptor type II (IL1R2) suppresses interleukin-1 activity. Another suppressor of IL1R activity is the interleukin-1 receptor antagonist (IL1R1A).
3D structures of interleukin receptor
Updated on 30-November-2014 {{#tree:id=OrganizedByTopic|openlevels=0|
Interleukin receptor type I
- Interleukin-2 receptor
- Interleukin-4 receptor
- Interleukin-5 receptor
- Interleukin-6 receptor or gp130
- 1i1r – hIL6R β subunit + interleukin-6 homolog
- 1pvh - hIL6R β subunit + leukemia inhILbitory factor
- 2hmh - mI6R β subunit + suppressor of cytokine signaling 3 – mouse
- 4gl9 - mI6R β subunit + suppressor of cytokine signaling 3 + tyrosine-protein kinase
- 3l5i, 3l5j, 3l5h - hIL6R β subunit
- 1n26 - hIL6R α subunit
- 2arw - hIL6R α subunit - NMR
- 1p9m - hIL6R α + β subunits + interleukin-6
- 1i1r – hIL6R β subunit + interleukin-6 homolog
- Interleukin-7 receptor
- Interleukin-13 receptor
- Interleukin-15 receptor
- Interleukin-17 receptor
- Interleukin-21 receptor
- 3tgx – hIL21R extracellular domain (mutant) + interleukin-21
Interleukin receptor type II
- Interleukin-10 receptor
- Interleukin-20 receptor
- 4doh - hIL20R α,β subunit + interleukin-20
- 4doh - hIL20R α,β subunit + interleukin-20
- Interleukin-22 receptor
- Interleukin-28 receptor
Interleukin receptor of immunoglobulin family
- Interleukin-1 receptor (CD121a, CD121b)
- 1itb – hI1R1 extracellular domain + interleukin-1 β – human
- 1ira- hI1R1 extracellular domain + I1R1A
- 1g0y - hI1R1 extracellular domain + I1R1A peptide
- 3o4o - hI1R2 + interleukin-1 β
- 4dep – hIL1R1 extracellular domain + interleukin-1 β + + interleukin-1 accessory protein
- 4gaf – hIL1R1 extracellular domain + IL1β/IL1RA
- 1itb – hI1R1 extracellular domain + interleukin-1 β – human
