Penicillin acylase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 6: Line 6:
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
[[1pnk]], [[1pnl]], [[1pnm]], [[1gk9]] – EcPAH – ''Escherichia coli''<br />
+
*Penicillin acylase
-
[[1gkf]], [[1h2g]], [[1jx9]] - EcPAH α + β (mutant) subunits <br />
+
-
[[1e3a]] – EcPAH precursor α + β (mutant) subunits<br />
+
-
[[3pva]], [[2pva]] – PAH – ''Lysinibacillus sphaericus''<br />
+
-
[[2iwm]], [[2quy]] - BsPAH (mutant) – ''Bacillus sphaericus''<br />
+
-
[[3mji]] - BsPAH <br />
+
-
[[2oqc]] - PAH – ''Bacillus subtilis''<br />
+
-
[[3k3w]], [[3ml0]] - PAH precursor – ''Alcaligenes faecalis''
+
-
===Penicillin acylase complex===
+
**[[1pnk]], [[1pnl]], [[1pnm]], [[1gk9]] – EcPAH – ''Escherichia coli''<br />
 +
**[[1gkf]], [[1h2g]], [[1jx9]] - EcPAH α + β (mutant) subunits <br />
 +
**[[1e3a]] – EcPAH precursor α + β (mutant) subunits<br />
 +
**[[3pva]], [[2pva]] – PAH – ''Lysinibacillus sphaericus''<br />
 +
**[[2iwm]], [[2quy]] - BsPAH (mutant) – ''Bacillus sphaericus''<br />
 +
**[[3mji]] - BsPAH <br />
 +
**[[2oqc]] - PAH – ''Bacillus subtilis''<br />
 +
**[[3k3w]], [[3ml0]] - PAH precursor – ''Alcaligenes faecalis''
-
[[1fxh]], [[1k5q]] - EcPAH α + β (mutant) subunits + PA<br />
+
*Penicillin acylase complex
-
[[1fxv]], [[1gm7]] - EcPAH α + β (mutant) subunits + penicillin<br />
+
-
[[1gm9]] - EcPAH α + β (mutant) subunits + penicillin derivative<br />
+
-
[[1gm8]], [[1k5s]], [[1kec]] - EcPAH α + β (mutant) subunits + PA derivative<br />
+
-
[[1ai4]], [[1ai5]], [[1ai6]], [[1ajn]], [[1ajp]], [[1ajq]], [[1k7d]] – EcPAH + PA derivative<br />
+
-
[[1ai7]] – EcPAH + phenol<br />
+
-
[[2z71]] - BsPAH (mutant) + penicillin
+
 +
**[[1fxh]], [[1k5q]] - EcPAH α + β (mutant) subunits + PA<br />
 +
**[[1fxv]], [[1gm7]] - EcPAH α + β (mutant) subunits + penicillin<br />
 +
**[[1gm9]] - EcPAH α + β (mutant) subunits + penicillin derivative<br />
 +
**[[1gm8]], [[1k5s]], [[1kec]] - EcPAH α + β (mutant) subunits + PA derivative<br />
 +
**[[1ai4]], [[1ai5]], [[1ai6]], [[1ajn]], [[1ajp]], [[1ajq]], [[1k7d]] – EcPAH + PA derivative<br />
 +
**[[1ai7]] – EcPAH + phenol<br />
 +
**[[2z71]] - BsPAH (mutant) + penicillin
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:03, 2 December 2014

Template:STRUCTURE 1fxv

Penicillin acylase (PAH) catalyzes the conversion of penicillin to 6-amino-penicillanate and phenylacetate (PA). PAH contains 2 non-identical subunits. The larger β subunit contains a phenylmethylsulfonyl residue which is required for enzymatic activity. PAH participates in penicillin and cephalosporin biosynthesis. PAH is used commercially for production of semi-synthetic penicillins.

3D structures of penicillin acylase

Updated on 02-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Penicillin_acylase"
Personal tools