4r7j
From Proteopedia
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| - | ''' | + | ==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase with the Internal Deletion Containing CBS Domain from Campylobacter jejuni== |
| - | + | <StructureSection load='4r7j' size='340' side='right' caption='[[4r7j]], [[Resolution|resolution]] 2.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4r7j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R7J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mz1|4mz1]], [[4mz8|4mz8]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r7j RCSB], [http://www.ebi.ac.uk/pdbsum/4r7j PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q0P9J4_CAMJE Q0P9J4_CAMJE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: IMP dehydrogenase]] | ||
| + | [[Category: Andesrson, W F]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Csgid]] | ||
| + | [[Category: Gu, M]] | ||
| + | [[Category: Hedstrom, L]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Kim, Y]] | ||
| + | [[Category: Makowska-Grzyska, M]] | ||
| + | [[Category: Alpha-beta structure]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: National institute of allergy and infectious disease]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Tim barrel]] | ||
Revision as of 14:26, 5 January 2015
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase with the Internal Deletion Containing CBS Domain from Campylobacter jejuni
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