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1dy9

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1dy9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_(isolate_taiwan) Hepatitis c virus (isolate taiwan)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DY9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1dy9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_(isolate_taiwan) Hepatitis c virus (isolate taiwan)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DY9 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2ZF:N-(TERT-BUTOXYCARBONYL)-L-ALPHA-GLUTAMYL-N-[(1R)-1-(CARBOXYCARBONYL)-3,3-DIFLUOROPROPYL]-L-LEUCINAMIDE'>2ZF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2ZF:N-(TERT-BUTOXYCARBONYL)-L-ALPHA-GLUTAMYL-N-[(1R)-1-(CARBOXYCARBONYL)-3,3-DIFLUOROPROPYL]-L-LEUCINAMIDE'>2ZF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dxp|1dxp]], [[1dy8|1dy8]], [[1jxp|1jxp]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dxp|1dxp]], [[1dy8|1dy8]], [[1jxp|1jxp]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31645 Hepatitis C virus (isolate Taiwan)])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31645 Hepatitis C virus (isolate Taiwan)])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1dy9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1dy9 PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Colarusso, S.]]
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[[Category: Colarusso, S]]
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[[Category: Francesco, R De.]]
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[[Category: Francesco, R De]]
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[[Category: Marco, S Di.]]
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[[Category: Marco, S Di]]
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[[Category: Matassa, V G.]]
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[[Category: Matassa, V G]]
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[[Category: Narjes, F.]]
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[[Category: Narjes, F]]
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[[Category: Rizzi, M.]]
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[[Category: Rizzi, M]]
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[[Category: Sollazzo, M.]]
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[[Category: Sollazzo, M]]
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[[Category: Volpari, C.]]
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[[Category: Volpari, C]]
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[[Category: Walsh, M.]]
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[[Category: Walsh, M]]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 23:16, 22 December 2014

Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor I)

1dy9, resolution 2.10Å

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