3wi3

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wi3]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WI3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wi3]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WI3 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wi3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wi3 RCSB], [http://www.ebi.ac.uk/pdbsum/3wi3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wi3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wi3 RCSB], [http://www.ebi.ac.uk/pdbsum/3wi3 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SLD3_YEAST SLD3_YEAST]] Required for loading and maintenance of stable association of CDC45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal regulation of origin firing. Required for the association of PSF1 with origins.<ref>PMID:11296242</ref> <ref>PMID:12730134</ref> <ref>PMID:21487389</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Araki, H.]]
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[[Category: Araki, H]]
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[[Category: Itou, H.]]
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[[Category: Itou, H]]
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[[Category: Shirakihara, Y.]]
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[[Category: Shirakihara, Y]]
[[Category: Alpha helical]]
[[Category: Alpha helical]]
[[Category: Cdc45-binding]]
[[Category: Cdc45-binding]]
[[Category: Replication regulator]]
[[Category: Replication regulator]]

Revision as of 00:41, 25 December 2014

Crystal Structure of the Sld3/Treslin domain from yeast Sld3

3wi3, resolution 2.40Å

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