This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4hus

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hus]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hus]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUS FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VIR:VIRGINIAMYCIN+M1'>VIR</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VIR:VIRGINIAMYCIN+M1'>VIR</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hur|4hur]], [[4e8l|4e8l]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hur|4hur]], [[4e8l|4e8l]]</td></tr>
-
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vat ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vat ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hus OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hus RCSB], [http://www.ebi.ac.uk/pdbsum/4hus PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hus OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hus RCSB], [http://www.ebi.ac.uk/pdbsum/4hus PDBsum]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/VATA_STAAU VATA_STAAU]] Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Anderson, W F.]]
+
[[Category: Anderson, W F]]
-
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+
[[Category: Structural genomic]]
-
[[Category: Courvalin, P.]]
+
[[Category: Courvalin, P]]
-
[[Category: Evdokimova, E.]]
+
[[Category: Evdokimova, E]]
-
[[Category: Krishnamoorthy, M.]]
+
[[Category: Krishnamoorthy, M]]
-
[[Category: Leo, R Di.]]
+
[[Category: Leo, R Di]]
-
[[Category: Minasov, G.]]
+
[[Category: Minasov, G]]
-
[[Category: Savchenko, A.]]
+
[[Category: Savchenko, A]]
-
[[Category: Stogios, P J.]]
+
[[Category: Stogios, P J]]
-
[[Category: Wawrzak, Z.]]
+
[[Category: Wawrzak, Z]]
-
[[Category: Yim, V.]]
+
[[Category: Yim, V]]
[[Category: Acetyl coenzyme some]]
[[Category: Acetyl coenzyme some]]
[[Category: Antibiotic resistance]]
[[Category: Antibiotic resistance]]
Line 42: Line 44:
[[Category: Streptogramin group a antibiotic acetyltransferase]]
[[Category: Streptogramin group a antibiotic acetyltransferase]]
[[Category: Streptogramin group a antibiotic]]
[[Category: Streptogramin group a antibiotic]]
-
[[Category: Structural genomic]]
 
[[Category: Transferase-antibiotic complex]]
[[Category: Transferase-antibiotic complex]]
[[Category: Virginiamycin m1]]
[[Category: Virginiamycin m1]]

Revision as of 11:21, 24 December 2014

Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with virginiamycin M1

4hus, resolution 2.36Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4hus"
Personal tools