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4c1f
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4c1f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C1F FirstGlance]. <br> | <table><tr><td colspan='2'>[[4c1f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C1F FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bz3|4bz3]], [[4c09|4c09]], [[4c1c|4c1c]], [[4c1d|4c1d]], [[4c1e|4c1e]], [[4c1g|4c1g]], [[4c1h|4c1h]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bz3|4bz3]], [[4c09|4c09]], [[4c1c|4c1c]], [[4c1d|4c1d]], [[4c1e|4c1e]], [[4c1g|4c1g]], [[4c1h|4c1h]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c1f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c1f RCSB], [http://www.ebi.ac.uk/pdbsum/4c1f PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c1f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c1f RCSB], [http://www.ebi.ac.uk/pdbsum/4c1f PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BLAB_SERMA BLAB_SERMA]] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| - | [[Category: Brem, J | + | [[Category: Brem, J]] |
| - | [[Category: McDonough, M A | + | [[Category: McDonough, M A]] |
| - | [[Category: Schofield, C J | + | [[Category: Schofield, C J]] |
| - | [[Category: Zollman, D | + | [[Category: Zollman, D]] |
| - | [[Category: VanBerkel, S S | + | [[Category: VanBerkel, S S]] |
[[Category: Antibiotic resistance]] | [[Category: Antibiotic resistance]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Mbl]] | [[Category: Mbl]] | ||
[[Category: Metallo-beta-lactamase]] | [[Category: Metallo-beta-lactamase]] | ||
Revision as of 21:13, 25 December 2014
Crystal structure of the metallo-beta-lactamase IMP-1 with L-captopril
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