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3wyk

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'''Unreleased structure'''
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==Crystal structure of the catalytic domain of PDE10A complexed with 3-(1-phenyl-1H-pyrazol-5-yl)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one==
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<StructureSection load='3wyk' size='340' side='right' caption='[[3wyk]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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The entry 3wyk is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3wyk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WYK FirstGlance]. <br>
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Authors: Oki, H., Hayano, Y.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3KG:3-(1-PHENYL-1H-PYRAZOL-5-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]PYRIDAZIN-4(1H)-ONE'>3KG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wym|3wym]], [[3wyl|3wyl]]</td></tr>
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Description: Crystal structure of the catalytic domain of PDE10A complexed with 3-(1-phenyl-1H-pyrazol-5-yl)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wyk RCSB], [http://www.ebi.ac.uk/pdbsum/3wyk PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Hayano, Y]]
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[[Category: Oki, H]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 12:47, 19 November 2014

Crystal structure of the catalytic domain of PDE10A complexed with 3-(1-phenyl-1H-pyrazol-5-yl)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one

3wyk, resolution 2.50Å

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