Signal recognition particle receptor

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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
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==3D structures of SRPR==
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==3D structures of signal recognition particle receptor==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===SRPR===
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*Signal recognition particle receptor
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[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
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**[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
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[[2fh5]] - hSRPR α+β subunits + GTP – human<br />
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**[[2fh5]] - hSRPR α+β subunits + GTP – human<br />
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[[2ged]] - ySRPR β subunit (mutant)<br />
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**[[2ged]] - ySRPR β subunit (mutant)<br />
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[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
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**[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
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[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
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**[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
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===SRPR FtsY===
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*Signal recognition particle receptor FtsY
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[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
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[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
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[[2yhs]], [[2qy9]], [[1fts]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
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[[2q9a]] – EcSRPR FtsY <br />
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[[2q9c]], [[2q9b]] – EcSRPR FtsY NG domain + GMPPNP<br />
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[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
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[[2xxa]] - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA<br />
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[[3zn8]] - EcSRPR FtsY NG domain + signal recognition particle protein 54 NG domain + 4.5SRNA + dipeptidyl aminopeptidase B<br />
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[[2j7p]], [[1rj9]], [[1okk]] – TaSRPR FtsY NG domain + signal recognition particle protein – ''Thermus aquaticus''<br />
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[[2cnw]] – TaSRPR FtsY NG domain + signal recognition particle protein + GDP<br />
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[[4c7o]] – EcFtsY + EcSRP + SRP RNA<br />
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[[2xkv]] – EcFtsY + EcSRP NG+M domains + 4.5S RNA<br />
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**[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
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**[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
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**[[2yhs]], [[2qy9]], [[1fts]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
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**[[2q9a]] – EcSRPR FtsY <br />
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**[[2q9c]], [[2q9b]] – EcSRPR FtsY NG domain + GMPPNP<br />
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**[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
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**[[2xxa]] - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA<br />
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**[[3zn8]] - EcSRPR FtsY NG domain + signal recognition particle protein 54 NG domain + 4.5SRNA + dipeptidyl aminopeptidase B<br />
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**[[2j7p]], [[1rj9]], [[1okk]] – TaSRPR FtsY NG domain + signal recognition particle protein – ''Thermus aquaticus''<br />
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**[[2cnw]] – TaSRPR FtsY NG domain + signal recognition particle protein + GDP<br />
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**[[4c7o]] – EcFtsY + EcSRP + SRP RNA<br />
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**[[2xkv]] – EcFtsY + EcSRP NG+M domains + 4.5S RNA<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:30, 10 December 2014

Human SRPR α (grey) and β subunit (green) complex with GTP (stick model) and Mg+2 (green) ion 2fh5

Drag the structure with the mouse to rotate

Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.

3D structures of signal recognition particle receptor

Updated on 10-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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