Spermidine Synthase
From Proteopedia
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *Spermidine synthase | |
| - | [[1inl]] – TmSPS – ''Thermotoga maritima''<br /> | + | **[[1inl]] – TmSPS – ''Thermotoga maritima''<br /> |
| - | [[1mjf]] – SPS – ''Pyrococcus furiosus''<br /> | + | **[[1mjf]] – SPS – ''Pyrococcus furiosus''<br /> |
| - | [[2e5w]], [[2zsu]] - SPS – ''Pyrococcus horikishii''<br /> | + | **[[2e5w]], [[2zsu]] - SPS – ''Pyrococcus horikishii''<br /> |
| - | [[1iy9]] – SPS – ''Bacillus subtilis''<br /> | + | **[[1iy9]] – SPS – ''Bacillus subtilis''<br /> |
| - | [[1xj5]], [[2q41]] – SPS – ''Arabidopsis thaliana''<br /> | + | **[[1xj5]], [[2q41]] – SPS – ''Arabidopsis thaliana''<br /> |
| - | [[2b2c]] – SPS – ''Caenorhabditis elegans''<br /> | + | **[[2b2c]] – SPS – ''Caenorhabditis elegans''<br /> |
| - | [[2o05]], [[2o06]], [[2o07]], [[2o0l]] – SPS – human<br /> | + | **[[2o05]], [[2o06]], [[2o07]], [[2o0l]] – SPS – human<br /> |
| - | [[2cmg]], [[2cmh]] – SPS – ''Helicobacter pylori''<br /> | + | **[[2cmg]], [[2cmh]] – SPS – ''Helicobacter pylori''<br /> |
| - | [[2pss]] – PfSPS – ''Plasmodium falciparum''<br /> | + | **[[2pss]] – PfSPS – ''Plasmodium falciparum''<br /> |
| - | [[3o4f]] – SPS – ''Escherichia coli''<br /> | + | **[[3o4f]] – SPS – ''Escherichia coli''<br /> |
| - | [[3bwc]] - TcSPS – ''Trypanosoma cruzi''<br /> | + | **[[3bwc]] - TcSPS – ''Trypanosoma cruzi''<br /> |
| - | + | *Binary complexes of spermidine synthase | |
| - | [[1jq3]] – TmSPS + transition state analog<br /> | + | **[[1jq3]] – TmSPS + transition state analog<br /> |
| - | [[2hte]], [[2pt6]] - PfSPS + methylthioadenosine <br /> | + | **[[2hte]], [[2pt6]] - PfSPS + methylthioadenosine <br /> |
| - | [[2i7c]] - PfSPS + transition state analog<br /> | + | **[[2i7c]] - PfSPS + transition state analog<br /> |
| - | [[2pwp]] - PfSPS + spermidine<br /> | + | **[[2pwp]] - PfSPS + spermidine<br /> |
| - | [[3b7p]] - PfSPS + spermine<br /> | + | **[[3b7p]] - PfSPS + spermine<br /> |
| - | [[3bwc]] - TcSPS + SAM <br /> | + | **[[3bwc]] - TcSPS + SAM <br /> |
| - | [[3rw9]] - hSPS + SAH<br /> | + | **[[3rw9]] - hSPS + SAH<br /> |
| - | [[3anx]] – SPS + methylthioadenosine – ''Thermus thermophilus''<br /> | + | **[[3anx]] – SPS + methylthioadenosine – ''Thermus thermophilus''<br /> |
| - | + | *Ternary complexes of spermidine synthase | |
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| + | **[[3c6k]] - hSPS + methylthioadenosine + spermidine<br /> | ||
| + | **[[3c6m]] - hSPS + methylthioadenosine + spermine<br /> | ||
| + | **[[2pt6]], [[3rie]] - PfSPS + inhibitor + methylthioadenosine<br /> | ||
| + | **[[2pt9]] - PfSPS + inhibitor + SAM derivative<br /> | ||
| + | }} | ||
Created with the participation of [[User:Lindsey Butler|Lindsey Butler]]. | Created with the participation of [[User:Lindsey Butler|Lindsey Butler]]. | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:00, 10 December 2014
Under construction!
Polyamines are essential in all branches of life. Spermidine synthase (putrescine aminopropyltransferase, PAPT) catalyzes the biosynthesis of spermidine, a ubiquitous polyamine. 1inl - The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution. The structure of TmPAPT in a complex with adoDATO (1jq3) can also be found on this site.
3D structures of spermidine synthase
Updated on 10-December-2014
Created with the participation of Lindsey Butler.
