Talin
From Proteopedia
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | * Talin subdomains | |
| - | [[2x0c]], [[2kbb]], [[3dyj]], [[1sj7]], [[1sj8]] – mTal rod – mouse<br /> | + | **[[2x0c]], [[2kbb]], [[3dyj]], [[1sj7]], [[1sj8]] – mTal rod – mouse<br /> |
| - | [[2kma]] – mTal F0F1 – NMR<br /> | + | **[[2kma]] – mTal F0F1 – NMR<br /> |
| - | [[2kc1]] - mTal F0 – NMR<br /> | + | **[[2kc1]] - mTal F0 – NMR<br /> |
| - | [[2kc2]] - mTal F1 – NMR<br /> | + | **[[2kc2]] - mTal F1 – NMR<br /> |
| - | [[2hrj]] - cTal F2 – NMR <br /> | + | **[[2hrj]] - cTal F2 – NMR <br /> |
| - | [[1mix]] – cTal F2F3<br /> | + | **[[1mix]] – cTal F2F3<br /> |
| - | [[4f7g]] - mTal F2F3 + rod segment domain<br /> | + | **[[4f7g]] - mTal F2F3 + rod segment domain<br /> |
| - | [[2kgx]] – mTal F3+mTal fragment – NMR<br /> | + | **[[2kgx]] – mTal F3+mTal fragment – NMR<br /> |
| - | [[3ivf]] – mTal FERM domain<br /> | + | **[[3ivf]] – mTal FERM domain<br /> |
| - | [[2l7n]] – mTal B – NMR<br /> | + | **[[2l7n]] – mTal B – NMR<br /> |
| - | [[2l10]] – mTal C - NMR<br /> | + | **[[2l10]] – mTal C - NMR<br /> |
| - | [[2lqg]] - mTal R4 helix – NMR<br /> | + | **[[2lqg]] - mTal R4 helix – NMR<br /> |
| - | + | * Talin integrin-binding sites | |
| - | [[2jsw]], [[2qdq]] – mTal IBS – NMR<br /> | + | **[[2jsw]], [[2qdq]] – mTal IBS – NMR<br /> |
| - | [[3g9w]] – mTal2 F2F3+integrin tail<br /> | + | **[[3g9w]] – mTal2 F2F3+integrin tail<br /> |
| - | [[1miz]], [[1mk7]], [[1mk9]] - hTal+integrin tail<br /> | + | **[[1miz]], [[1mk7]], [[1mk9]] - hTal+integrin tail<br /> |
| - | [[2h7d]], [[2h7e]] - cTal FERM F3+integrlin fragment – NMR <br /> | + | **[[2h7d]], [[2h7e]] - cTal FERM F3+integrlin fragment – NMR <br /> |
| - | [[3fyq]] – Tal rod IBS2 – ''Drosophila melanogaster'' | + | **[[3fyq]] – Tal rod IBS2 – ''Drosophila melanogaster'' |
| - | + | * Talin vinculin-binding sites | |
| + | |||
| + | **[[2kvp]], [[2b0h]] – mTal VBS3 – NMR<br /> | ||
| + | **[[1xwj]], [[1zvz]], [[1zw2]], [[1zw3]] - cTal VBS3+ vinculin head – chicken<br /> | ||
| + | **[[1u6h]] - cTal VBS2+ vinculin head<br /> | ||
| + | **[[1t01]] - cTal VBS1+ vinculin head<br /> | ||
| + | **[[1syq]] - hTal VBS1+ vinculin head – human<br /> | ||
| + | **[[1rkc]], [[3s90]] - hTal VBS3+ vinculin head<br /> | ||
| + | **[[1u89]], [[2l7a]] - mTal VBS2 – NMR<br /> | ||
| + | **[[4dj9]] – hTal VBS50 + vinculin head | ||
| + | |||
| + | *Talin phosphatidylinositol phosphate kinase binding sites | ||
| + | |||
| + | **[[1y19]] - mTal F2F3+ PIP kinase C-terminal<br /> | ||
| + | **[[2g35]] - mTal F3+PIP kinase peptide – NMR | ||
| + | |||
| + | *Layilin binding sites | ||
| + | |||
| + | **[[2k00]] - cTal F3+layilin fragment – NMR | ||
| + | }} | ||
| + | [[Category: Topic Page]] | ||
| - | [[2kvp]], [[2b0h]] – mTal VBS3 – NMR<br /> | ||
| - | [[1xwj]], [[1zvz]], [[1zw2]], [[1zw3]] - cTal VBS3+ vinculin head – chicken<br /> | ||
| - | [[1u6h]] - cTal VBS2+ vinculin head<br /> | ||
| - | [[1t01]] - cTal VBS1+ vinculin head<br /> | ||
| - | [[1syq]] - hTal VBS1+ vinculin head – human<br /> | ||
| - | [[1rkc]], [[3s90]] - hTal VBS3+ vinculin head<br /> | ||
| - | [[1u89]], [[2l7a]] - mTal VBS2 – NMR<br /> | ||
| - | [[4dj9]] – hTal VBS50 + vinculin head | ||
| - | === Talin PIP kinase binding sites === | ||
[[1y19]] - mTal F2F3+ PIP kinase C-terminal<br /> | [[1y19]] - mTal F2F3+ PIP kinase C-terminal<br /> | ||
Revision as of 08:54, 11 December 2014
Talin is involved in cell-cell contacts. It links integrins to actin. It contains a C-terminal rod domain with integrin binding sites (IBS) and actin binding sites (ABS) and N-terminal FERM domain with subdomains F0-F3. The F3 subdomains interacts with integrin. Talin contains 3 Vinculin binding sites VBS1-VBS3.
3D Structures of Talin
Updated on 11-December-2014
2g35 - mTal F3+PIP kinase peptide – NMR
Layilin binding sites
2k00 - cTal F3+layilin fragment – NMR
