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4mtz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mtz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MTZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4mtz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MTZ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0BU:8-({3-[({3-[(4,6,8-TRISULFONAPHTHALEN-1-YL)CARBAMOYL]PHENYL}CARBAMOYL)AMINO]BENZOYL}AMINO)NAPHTHALENE-1,3,5-TRISULFONIC+ACID'>0BU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0BU:8-({3-[({3-[(4,6,8-TRISULFONAPHTHALEN-1-YL)CARBAMOYL]PHENYL}CARBAMOYL)AMINO]BENZOYL}AMINO)NAPHTHALENE-1,3,5-TRISULFONIC+ACID'>0BU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mtz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mtz RCSB], [http://www.ebi.ac.uk/pdbsum/4mtz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mtz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mtz RCSB], [http://www.ebi.ac.uk/pdbsum/4mtz PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/XIAP_HUMAN XIAP_HUMAN]] Defects in XIAP are the cause of lymphoproliferative syndrome X-linked type 2 (XLP2) [MIM:[http://omim.org/entry/300635 300635]]. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma.<ref>PMID:17080092</ref> | [[http://www.uniprot.org/uniprot/XIAP_HUMAN XIAP_HUMAN]] Defects in XIAP are the cause of lymphoproliferative syndrome X-linked type 2 (XLP2) [MIM:[http://omim.org/entry/300635 300635]]. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma.<ref>PMID:17080092</ref> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bolognesi, M | + | [[Category: Bolognesi, M]] |
| - | [[Category: Cossu, F | + | [[Category: Cossu, F]] |
| - | [[Category: Grassi, S | + | [[Category: Grassi, S]] |
| - | [[Category: Mastrangelo, E | + | [[Category: Mastrangelo, E]] |
| - | [[Category: Milani, M | + | [[Category: Milani, M]] |
[[Category: Anti-apoptotic]] | [[Category: Anti-apoptotic]] | ||
[[Category: Bir domain]] | [[Category: Bir domain]] | ||
[[Category: Ligase-ligase inhibitor complex]] | [[Category: Ligase-ligase inhibitor complex]] | ||
[[Category: Tab1]] | [[Category: Tab1]] | ||
Revision as of 09:45, 20 January 2015
Structure of XIAP-BIR1 in complex with NF023
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