1enn
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1enn |SIZE=350|CAPTION= <scene name='initialview01'>1enn</scene>, resolution 0.89Å | |PDB= 1enn |SIZE=350|CAPTION= <scene name='initialview01'>1enn</scene>, resolution 0.89Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1enn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1enn OCA], [http://www.ebi.ac.uk/pdbsum/1enn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1enn RCSB]</span> | ||
}} | }} | ||
| Line 24: | Line 27: | ||
[[Category: Soler-Lopez, M.]] | [[Category: Soler-Lopez, M.]] | ||
[[Category: Subirana, J A.]] | [[Category: Subirana, J A.]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: MG]] | ||
| - | [[Category: O]] | ||
[[Category: atomic resolution]] | [[Category: atomic resolution]] | ||
[[Category: b-dna]] | [[Category: b-dna]] | ||
| Line 33: | Line 33: | ||
[[Category: ion]] | [[Category: ion]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:06:08 2008'' |
Revision as of 17:06, 30 March 2008
| |||||||
| , resolution 0.89Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SOLVENT ORGANIZATION IN AN OLIGONUCLEOTIDE CRYSTAL: THE STRUCTURE OF D(GCGAATTCG)2 AT ATOMIC RESOLUTION
Overview
We describe the crystal structure of d(GCGAATTCG) determined by x-ray diffraction at atomic resolution level (0.89 A). The duplex structure is practically identical to that described at 2.05 A resolution (Van Meervelt, L., Vlieghe, D., Dautant, A., Gallois, B., Precigoux, G., and Kennard, O. (1995) Nature 374, 742-744), however about half of the phosphate groups show multiple conformations. The crystal has three regions with different solvent structure. One of them contains several ordered Mg(+2) ions and can be considered as an ionic crystal. A second region is formed by a network of ordered water molecules with a polygonal organization that binds three duplexes. The third region is formed by channels of solvent in which very few ordered solvent molecules are visible. The less ordered phosphates are found facing this channel. The latter region provides a view of DNA with highly movable charges, both negative phosphates and counterions, without a precise location.
About this Structure
1ENN is a Protein complex structure of sequences from [1]. This structure supersedes the now removed PDB entry 475D. Full crystallographic information is available from OCA.
Reference
Solvent organization in an oligonucleotide crystal. The structure of d(GCGAATTCG)2 at atomic resolution., Soler-Lopez M, Malinina L, Subirana JA, J Biol Chem. 2000 Jul 28;275(30):23034-44. PMID:10749874
Page seeded by OCA on Sun Mar 30 20:06:08 2008
