1jt6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jt6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JT6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jt6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JT6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jt0|1jt0]], [[1jty|1jty]], [[1jum|1jum]], [[1jup|1jup]], [[1jus|1jus]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jt0|1jt0]], [[1jty|1jty]], [[1jum|1jum]], [[1jup|1jup]], [[1jus|1jus]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jt6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jt6 RCSB], [http://www.ebi.ac.uk/pdbsum/1jt6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jt6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jt6 RCSB], [http://www.ebi.ac.uk/pdbsum/1jt6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/QACR_STAAU QACR_STAAU]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Brennan, R G | + | [[Category: Brennan, R G]] |
| - | [[Category: Brown, M H | + | [[Category: Brown, M H]] |
| - | [[Category: Grkovic, S | + | [[Category: Grkovic, S]] |
| - | [[Category: Miller, M C | + | [[Category: Miller, M C]] |
| - | [[Category: Schumacher, M A | + | [[Category: Schumacher, M A]] |
| - | [[Category: Skurray, R A | + | [[Category: Skurray, R A]] |
[[Category: Mulitdrug resistance]] | [[Category: Mulitdrug resistance]] | ||
[[Category: Mutlidrug binding recognition]] | [[Category: Mutlidrug binding recognition]] | ||
Revision as of 23:14, 24 December 2014
Crystal structure of the multidrug binding protein QacR bound to dequalinium
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