1igw
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1igw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGW FirstGlance]. <br> | <table><tr><td colspan='2'>[[1igw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGW FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aceA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aceA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_lyase Isocitrate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.1 4.1.3.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_lyase Isocitrate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.1 4.1.3.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igw RCSB], [http://www.ebi.ac.uk/pdbsum/1igw PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igw RCSB], [http://www.ebi.ac.uk/pdbsum/1igw PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACEA_ECOLI ACEA_ECOLI]] Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle. May be involved in the assimilation of one-carbon compounds via the isocitrate lyase-positive serine pathway (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Isocitrate lyase]] | [[Category: Isocitrate lyase]] | ||
| - | [[Category: Abeysinghe, I S.B | + | [[Category: Abeysinghe, I S.B]] |
| - | [[Category: Baker, P J | + | [[Category: Baker, P J]] |
| - | [[Category: Barynin, V | + | [[Category: Barynin, V]] |
| - | [[Category: Britton, K L | + | [[Category: Britton, K L]] |
| - | [[Category: Diehl, P | + | [[Category: Diehl, P]] |
| - | [[Category: Langridge, S J | + | [[Category: Langridge, S J]] |
| - | [[Category: McFadden, B A | + | [[Category: McFadden, B A]] |
| - | [[Category: Rice, D W | + | [[Category: Rice, D W]] |
| - | [[Category: Sedelnikova, S E | + | [[Category: Sedelnikova, S E]] |
| - | [[Category: Stillman, T J | + | [[Category: Stillman, T J]] |
| - | [[Category: Weeradechapon, K | + | [[Category: Weeradechapon, K]] |
[[Category: Beta barrel]] | [[Category: Beta barrel]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
Revision as of 16:21, 25 December 2014
Crystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia coli
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