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1fpu

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fpu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fpu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FPU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRC:N-[4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-3-PYRIDINECARBOXAMIDE'>PRC</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRC:N-[4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-3-PYRIDINECARBOXAMIDE'>PRC</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fpu RCSB], [http://www.ebi.ac.uk/pdbsum/1fpu PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fpu RCSB], [http://www.ebi.ac.uk/pdbsum/1fpu PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Bornmann, W.]]
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[[Category: Bornmann, W]]
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[[Category: Clarkson, B.]]
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[[Category: Clarkson, B]]
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[[Category: Kuriyan, J.]]
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[[Category: Kuriyan, J]]
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[[Category: Miller, W T.]]
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[[Category: Miller, W T]]
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[[Category: Pellicena, P.]]
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[[Category: Pellicena, P]]
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[[Category: Schindler, T.]]
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[[Category: Schindler, T]]
[[Category: Activation loop]]
[[Category: Activation loop]]
[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Kinase inhibitor]]
[[Category: Kinase inhibitor]]
[[Category: Sti-571]]
[[Category: Sti-571]]
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[[Category: Transferase]]
 

Revision as of 20:52, 22 December 2014

CRYSTAL STRUCTURE OF ABL KINASE DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR

1fpu, resolution 2.40Å

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