UDP-galactose 4-epimerase

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'''UDP-galactose 4-epimerase''' (GalE) reversibly converts UDP-galactose to UDP-glucose. GalE catalyzes the last step in galactose metabolism. GalE uses NAD+ as a cofactor.
'''UDP-galactose 4-epimerase''' (GalE) reversibly converts UDP-galactose to UDP-glucose. GalE catalyzes the last step in galactose metabolism. GalE uses NAD+ as a cofactor.
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</StructureSection>
==3D structures of UDP-galactose 4 epimerase==
==3D structures of UDP-galactose 4 epimerase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===GalE with no ligand===
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*UDP-galactose 4-epimerase with no ligand
-
[[1ek5]] - hGalE + NAD - human<br />
+
**[[1ek5]] - hGalE + NAD - human<br />
-
[[2c20]] - GalE + NAD – ''Bacillus anthracis''<br />
+
**[[2c20]] - GalE + NAD – ''Bacillus anthracis''<br />
-
[[2p5u]], [[2p5y]] - GalE + NAD – ''Thermus thermophilus''<br />
+
**[[2p5u]], [[2p5y]] - GalE + NAD – ''Thermus thermophilus''<br />
-
[[3enk]] - GalE + NAD – ''Burkholderia pseudo mallei''<br />
+
**[[3enk]] - GalE + NAD – ''Burkholderia pseudo mallei''<br />
-
[[3icp]], [[3ko8]] - PcGalE + NAD – ''Pyrobaculum calidifontis''<br />
+
**[[3icp]], [[3ko8]] - PcGalE + NAD – ''Pyrobaculum calidifontis''<br />
-
===GalE complexes===
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*UDP-galactose 4-epimerase complexes
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+
-
[[1nah]], [[1nai]] – EcGalE + NAD + UDP – ''Escherichia coli''<br />
+
-
[[1gy8]] - EcGalE (mutant) + NAD + UDP <br />
+
-
[[1xel]], [[1udb]], [[1a9y]] - EcGalE + NAD + UDP-glucose<br />
+
-
[[1a9z]], [[1lrl]] - EcGalE (mutant) + NAD + UDP-glucose<br />
+
-
[[1uda]] - EcGalE + NAD + UDP-galactose<br />
+
-
[[1lrj]] - EcGalE + NAD + UDP-acetylglucosamine<br />
+
-
[[1lrj]], [[1lrk]] - EcGalE (mutant) + NAD + UDP-acetylglucosamine<br />
+
-
[[1udc]] - EcGalE + NAD + UDP-mannose<br />
+
-
[[1kvr]], [[1kvs]], [[1kvt]], [[1kvu]], [[1kvq]] – EcGalE (mutant) + NAD + UDP-phenol<br />
+
-
[[2udp]] - EcGalE + NAD + UDP-phenol<br />
+
-
[[1ek6]] - hGalE + NAD + UDP-glucose<br />
+
-
[[1hzj]] - hGalE + NAD + UDP-glucosamine<br />
+
-
[[1i3k]] - hGalE (mutant) + NAD + UDP-glucose<br />
+
-
[[1i3l]], [[2cnb]] - hGalE (mutant) + NAD + UDP-galactose<br />
+
-
[[1i3m]], [[1i3n]] - hGalE (mutant) + NAD + UDP-acetylglucosamine<br />
+
-
[[3aw9]] - PcGalE (mutant) + NAD + UDP-galactopyranose <br />
+
 +
**[[1nah]], [[1nai]] – EcGalE + NAD + UDP – ''Escherichia coli''<br />
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**[[1gy8]] - EcGalE (mutant) + NAD + UDP <br />
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**[[1xel]], [[1udb]], [[1a9y]] - EcGalE + NAD + UDP-glucose<br />
 +
**[[1a9z]], [[1lrl]] - EcGalE (mutant) + NAD + UDP-glucose<br />
 +
**[[1uda]] - EcGalE + NAD + UDP-galactose<br />
 +
**[[1lrj]] - EcGalE + NAD + UDP-acetylglucosamine<br />
 +
**[[1lrj]], [[1lrk]] - EcGalE (mutant) + NAD + UDP-acetylglucosamine<br />
 +
**[[1udc]] - EcGalE + NAD + UDP-mannose<br />
 +
**[[1kvr]], [[1kvs]], [[1kvt]], [[1kvu]], [[1kvq]] – EcGalE (mutant) + NAD + UDP-phenol<br />
 +
**[[2udp]] - EcGalE + NAD + UDP-phenol<br />
 +
**[[1ek6]] - hGalE + NAD + UDP-glucose<br />
 +
**[[1hzj]] - hGalE + NAD + UDP-glucosamine<br />
 +
**[[1i3k]] - hGalE (mutant) + NAD + UDP-glucose<br />
 +
**[[1i3l]], [[2cnb]] - hGalE (mutant) + NAD + UDP-galactose<br />
 +
**[[1i3m]], [[1i3n]] - hGalE (mutant) + NAD + UDP-acetylglucosamine<br />
 +
**[[3aw9]] - PcGalE (mutant) + NAD + UDP-galactopyranose <br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:57, 17 December 2014

Structure of UDP-galactose 4 epimerase complex with NAD, UDP (stick model), PEG and Na+1 (purple) ions (PDB entry 1nah)

Drag the structure with the mouse to rotate

3D structures of UDP-galactose 4 epimerase

Updated on 17-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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