1iwg

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1iwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The November 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Multidrug Resistance Transporters'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_11 10.2210/rcsb_pdb/mom_2007_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWG FirstGlance]. <br>
<table><tr><td colspan='2'>[[1iwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The November 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Multidrug Resistance Transporters'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_11 10.2210/rcsb_pdb/mom_2007_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwg RCSB], [http://www.ebi.ac.uk/pdbsum/1iwg PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwg RCSB], [http://www.ebi.ac.uk/pdbsum/1iwg PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Multidrug Resistance Transporters]]
[[Category: Multidrug Resistance Transporters]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Murakami, S.]]
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[[Category: Murakami, S]]
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[[Category: Nakashima, R.]]
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[[Category: Nakashima, R]]
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[[Category: Yamaguchi, A.]]
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[[Category: Yamaguchi, A]]
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[[Category: Yamashita, E.]]
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[[Category: Yamashita, E]]
[[Category: Antiporter]]
[[Category: Antiporter]]
[[Category: Drug resistance]]
[[Category: Drug resistance]]

Revision as of 13:54, 24 December 2014

Crystal structure of Bacterial Multidrug Efflux transporter AcrB

1iwg, resolution 3.50Å

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