1k1g
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1k1g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K1G FirstGlance]. <br> | <table><tr><td colspan='2'>[[1k1g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K1G FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k1g RCSB], [http://www.ebi.ac.uk/pdbsum/1k1g PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k1g RCSB], [http://www.ebi.ac.uk/pdbsum/1k1g PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SF01_HUMAN SF01_HUMAN]] Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.<ref>PMID:8752089</ref> <ref>PMID:10449420</ref> <ref>PMID:9660765</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Bottomley, M J | + | [[Category: Bottomley, M J]] |
| - | [[Category: Houngninou-Molango, S | + | [[Category: Houngninou-Molango, S]] |
| - | [[Category: Kramer, A | + | [[Category: Kramer, A]] |
| - | [[Category: Liu, Z | + | [[Category: Liu, Z]] |
| - | [[Category: Luyten, I | + | [[Category: Luyten, I]] |
| - | [[Category: Messias, A C | + | [[Category: Messias, A C]] |
| - | [[Category: Sattler, M | + | [[Category: Sattler, M]] |
| - | [[Category: Sprangers, R | + | [[Category: Sprangers, R]] |
| - | [[Category: Zanier, K | + | [[Category: Zanier, K]] |
[[Category: Branch point sequence]] | [[Category: Branch point sequence]] | ||
[[Category: Complex e]] | [[Category: Complex e]] | ||
Revision as of 16:51, 25 December 2014
STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1
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