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1kej
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1kej]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KEJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KEJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1kej]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KEJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KEJ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DAD:2,3-DIDEOXYADENOSINE-5-TRIPHOSPHATE'>DAD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DAD:2,3-DIDEOXYADENOSINE-5-TRIPHOSPHATE'>DAD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jms|1jms]], [[1kdh|1kdh]], [[1bpy|1bpy]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jms|1jms]], [[1kdh|1kdh]], [[1bpy|1bpy]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_nucleotidylexotransferase DNA nucleotidylexotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.31 2.7.7.31] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_nucleotidylexotransferase DNA nucleotidylexotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.31 2.7.7.31] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kej OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kej RCSB], [http://www.ebi.ac.uk/pdbsum/1kej PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kej OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kej RCSB], [http://www.ebi.ac.uk/pdbsum/1kej PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: DNA nucleotidylexotransferase]] | [[Category: DNA nucleotidylexotransferase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Boule, J B | + | [[Category: Boule, J B]] |
| - | [[Category: Delarue, M | + | [[Category: Delarue, M]] |
| - | [[Category: Expert-Bezancon, N | + | [[Category: Expert-Bezancon, N]] |
| - | [[Category: Jourdan, N | + | [[Category: Jourdan, N]] |
| - | [[Category: Lescar, J | + | [[Category: Lescar, J]] |
| - | [[Category: Papanicolaou, C | + | [[Category: Papanicolaou, C]] |
| - | [[Category: Rougeon, F | + | [[Category: Rougeon, F]] |
| - | [[Category: Sukumar, N | + | [[Category: Sukumar, N]] |
[[Category: Nucleotidyl transferase]] | [[Category: Nucleotidyl transferase]] | ||
[[Category: Pol x family]] | [[Category: Pol x family]] | ||
[[Category: Polymerase]] | [[Category: Polymerase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 16:53, 25 December 2014
Crystal Structure of Murine Terminal Deoxynucleotidyl Transferase complexed with ddATP
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