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1k12

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1k12]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anguilla_anguilla Anguilla anguilla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K12 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K12 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1k12]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anguilla_anguilla Anguilla anguilla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K12 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K12 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k12 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k12 RCSB], [http://www.ebi.ac.uk/pdbsum/1k12 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k12 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k12 RCSB], [http://www.ebi.ac.uk/pdbsum/1k12 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FUCL_ANGAN FUCL_ANGAN]] Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.<ref>PMID:15207656</ref> <ref>PMID:12091873</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Anguilla anguilla]]
[[Category: Anguilla anguilla]]
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[[Category: Amzel, L M.]]
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[[Category: Amzel, L M]]
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[[Category: Bianchet, M A.]]
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[[Category: Bianchet, M A]]
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[[Category: Odom, E W.]]
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[[Category: Odom, E W]]
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[[Category: Vasta, G R.]]
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[[Category: Vasta, G R]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Protein carbohydrate complex]]
[[Category: Protein carbohydrate complex]]
[[Category: Sugar binding protein]]
[[Category: Sugar binding protein]]

Revision as of 14:19, 24 December 2014

Fucose Binding lectin

1k12, resolution 1.90Å

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