1evb

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|PDB= 1evb |SIZE=350|CAPTION= <scene name='initialview01'>1evb</scene>
|PDB= 1evb |SIZE=350|CAPTION= <scene name='initialview01'>1evb</scene>
|SITE=
|SITE=
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|LIGAND=
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|LIGAND= <scene name='pdbligand=ACB:3-METHYL-ASPARTIC+ACID'>ACB</scene>, <scene name='pdbligand=ADD:2,6,8-TRIMETHYL-3-AMINO-9-BENZYL-9-METHOXYNONANOIC+ACID'>ADD</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAM:N-METHYL-ALPHA-BETA-DEHYDROALANINE'>DAM</scene>, <scene name='pdbligand=ILG:GLUTAMYL+GROUP'>ILG</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=[[1eva|1EVA]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1evb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evb OCA], [http://www.ebi.ac.uk/pdbsum/1evb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1evb RCSB]</span>
}}
}}
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[[Category: phosphatase-1/-2a inhibitor]]
[[Category: phosphatase-1/-2a inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:00:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:10:18 2008''

Revision as of 17:10, 30 March 2008


PDB ID 1evb

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Ligands: , , , ,
Related: 1EVA


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Cyanobacterial toxin, phosphatase-1/-2A inhibitor, NMR


Overview

A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets.

About this Structure

1EVB is a Protein complex structure of sequences from Microcystis. Full crystallographic information is available from OCA.

Reference

Comparison of the solution structures of microcystin-LR and motuporin., Bagu JR, Sonnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF, Nat Struct Biol. 1995 Feb;2(2):114-6. PMID:7749913

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