1j7e
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J7E FirstGlance]. <br> | <table><tr><td colspan='2'>[[1j7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J7E FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JY:3-(2-{4-[2-(5-HYDROXY-2-METHYLENE-CYCLOHEXYLIDENE)-ETHYLIDENE]-7A-METHYL-OCTAHYDRO-INDEN-1-YL}-PROPYL)-PHENOL'>JY</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JY:3-(2-{4-[2-(5-HYDROXY-2-METHYLENE-CYCLOHEXYLIDENE)-ETHYLIDENE]-7A-METHYL-OCTAHYDRO-INDEN-1-YL}-PROPYL)-PHENOL'>JY</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j78|1j78]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j78|1j78]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j7e RCSB], [http://www.ebi.ac.uk/pdbsum/1j7e PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j7e RCSB], [http://www.ebi.ac.uk/pdbsum/1j7e PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VTDB_HUMAN VTDB_HUMAN]] Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Baelen, H Van | + | [[Category: Baelen, H Van]] |
| - | [[Category: Bouillon, R | + | [[Category: Bouillon, R]] |
| - | [[Category: Maeyer, M De | + | [[Category: Maeyer, M De]] |
| - | [[Category: Rabijns, A | + | [[Category: Rabijns, A]] |
| - | [[Category: Ranter, C De | + | [[Category: Ranter, C De]] |
| - | [[Category: Verboven, C | + | [[Category: Verboven, C]] |
[[Category: Gc-globulin]] | [[Category: Gc-globulin]] | ||
[[Category: Group-specific component]] | [[Category: Group-specific component]] | ||
Revision as of 14:50, 24 December 2014
A Structural Basis for the Unique Binding Features of the Human Vitamin D-binding Protein
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