1m7b

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1m7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M7B FirstGlance]. <br>
<table><tr><td colspan='2'>[[1m7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M7B FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rnd3 (amino acids 19-200) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rnd3 (amino acids 19-200) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m7b RCSB], [http://www.ebi.ac.uk/pdbsum/1m7b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m7b RCSB], [http://www.ebi.ac.uk/pdbsum/1m7b PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RND3_HUMAN RND3_HUMAN]] Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ahmadian, M R.]]
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[[Category: Ahmadian, M R]]
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[[Category: Blumenstein, L.]]
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[[Category: Blumenstein, L]]
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[[Category: Fiegen, D.]]
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[[Category: Fiegen, D]]
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[[Category: Stege, P.]]
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[[Category: Stege, P]]
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[[Category: Vetter, I R.]]
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[[Category: Vetter, I R]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
[[Category: Small gtpase]]
[[Category: Small gtpase]]

Revision as of 19:04, 25 December 2014

Crystal structure of Rnd3/RhoE: functional implications

1m7b, resolution 2.00Å

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