1fqx

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fqx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FQX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fqx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FQX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0ZT:N-{(2S,3S)-3-[(TERT-BUTOXYCARBONYL)AMINO]-2-HYDROXY-4-PHENYLBUTYL}-L-PHENYLALANYL-L-ALPHA-GLUTAMYL-L-PHENYLALANINAMIDE'>0ZT</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0ZT:N-{(2S,3S)-3-[(TERT-BUTOXYCARBONYL)AMINO]-2-HYDROXY-4-PHENYLBUTYL}-L-PHENYLALANYL-L-ALPHA-GLUTAMYL-L-PHENYLALANINAMIDE'>0ZT</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fqx RCSB], [http://www.ebi.ac.uk/pdbsum/1fqx PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fqx RCSB], [http://www.ebi.ac.uk/pdbsum/1fqx PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Brynda, J.]]
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[[Category: Brynda, J]]
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[[Category: Dohnalek, J.]]
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[[Category: Dohnalek, J]]
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[[Category: Duskova, J.]]
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[[Category: Duskova, J]]
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[[Category: Fabry, M.]]
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[[Category: Fabry, M]]
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[[Category: Hasek, J.]]
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[[Category: Hasek, J]]
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[[Category: Hradilek, M.]]
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[[Category: Hradilek, M]]
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[[Category: Konvalinka, J.]]
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[[Category: Konvalinka, J]]
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[[Category: Petrokova, H.]]
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[[Category: Petrokova, H]]
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[[Category: Sedlacek, J.]]
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[[Category: Sedlacek, J]]
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[[Category: Soucek, M.]]
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[[Category: Soucek, M]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Drug design]]
[[Category: Drug design]]

Revision as of 23:45, 22 December 2014

CRYSTAL STRUCTURE OF THE COMPLEX OF HIV-1 PROTEASE WITH A PEPTIDOMIMETIC INHIBITOR

1fqx, resolution 3.10Å

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