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1fqx
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1fqx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FQX FirstGlance]. <br> | <table><tr><td colspan='2'>[[1fqx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FQX FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0ZT:N-{(2S,3S)-3-[(TERT-BUTOXYCARBONYL)AMINO]-2-HYDROXY-4-PHENYLBUTYL}-L-PHENYLALANYL-L-ALPHA-GLUTAMYL-L-PHENYLALANINAMIDE'>0ZT</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0ZT:N-{(2S,3S)-3-[(TERT-BUTOXYCARBONYL)AMINO]-2-HYDROXY-4-PHENYLBUTYL}-L-PHENYLALANYL-L-ALPHA-GLUTAMYL-L-PHENYLALANINAMIDE'>0ZT</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fqx RCSB], [http://www.ebi.ac.uk/pdbsum/1fqx PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fqx RCSB], [http://www.ebi.ac.uk/pdbsum/1fqx PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Brynda, J | + | [[Category: Brynda, J]] |
| - | [[Category: Dohnalek, J | + | [[Category: Dohnalek, J]] |
| - | [[Category: Duskova, J | + | [[Category: Duskova, J]] |
| - | [[Category: Fabry, M | + | [[Category: Fabry, M]] |
| - | [[Category: Hasek, J | + | [[Category: Hasek, J]] |
| - | [[Category: Hradilek, M | + | [[Category: Hradilek, M]] |
| - | [[Category: Konvalinka, J | + | [[Category: Konvalinka, J]] |
| - | [[Category: Petrokova, H | + | [[Category: Petrokova, H]] |
| - | [[Category: Sedlacek, J | + | [[Category: Sedlacek, J]] |
| - | [[Category: Soucek, M | + | [[Category: Soucek, M]] |
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
Revision as of 23:45, 22 December 2014
CRYSTAL STRUCTURE OF THE COMPLEX OF HIV-1 PROTEASE WITH A PEPTIDOMIMETIC INHIBITOR
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Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Brynda, J | Dohnalek, J | Duskova, J | Fabry, M | Hasek, J | Hradilek, M | Konvalinka, J | Petrokova, H | Sedlacek, J | Soucek, M | Aspartyl protease | Drug design | Hiv | Hydrolase-hydrolase inhibitor complex | Hydroxyethylamine isostere | Inhibitor | Peptidomimetic | Protease
