This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1md7
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1md7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MD7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1md7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MD7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gpz|1gpz]], [[1md8|1md8]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gpz|1gpz]], [[1md8|1md8]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Complement_subcomponent_C1r Complement subcomponent C1r], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.41 3.4.21.41] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Complement_subcomponent_C1r Complement subcomponent C1r], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.41 3.4.21.41] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1md7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1md7 RCSB], [http://www.ebi.ac.uk/pdbsum/1md7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1md7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1md7 RCSB], [http://www.ebi.ac.uk/pdbsum/1md7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/C1R_HUMAN C1R_HUMAN]] C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 32: | Line 34: | ||
[[Category: Complement subcomponent C1r]] | [[Category: Complement subcomponent C1r]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arlaud, G J | + | [[Category: Arlaud, G J]] |
| - | [[Category: Budayova-Spano, M | + | [[Category: Budayova-Spano, M]] |
| - | [[Category: Fontecilla-Camps, J | + | [[Category: Fontecilla-Camps, J]] |
| - | [[Category: Gaboriaud, C | + | [[Category: Gaboriaud, C]] |
| - | [[Category: Grabarse, W | + | [[Category: Grabarse, W]] |
| - | [[Category: Hillen, H | + | [[Category: Hillen, H]] |
| - | [[Category: Lacroix, M | + | [[Category: Lacroix, M]] |
| - | [[Category: Schmidt, M | + | [[Category: Schmidt, M]] |
| - | [[Category: Thielens, N M | + | [[Category: Thielens, N M]] |
[[Category: Activation]] | [[Category: Activation]] | ||
[[Category: Complement]] | [[Category: Complement]] | ||
Revision as of 22:46, 24 December 2014
Monomeric structure of the zymogen of complement protease C1r
| |||||||||||
