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1j72

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j72]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J72 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J72 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j72]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J72 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J72 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j72 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j72 RCSB], [http://www.ebi.ac.uk/pdbsum/1j72 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j72 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j72 RCSB], [http://www.ebi.ac.uk/pdbsum/1j72 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CAPG_HUMAN CAPG_HUMAN]] Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Almo, S C.]]
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[[Category: Almo, S C]]
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[[Category: Southwick, F S.]]
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[[Category: Southwick, F S]]
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[[Category: Storokopytov, B.]]
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[[Category: Storokopytov, B]]
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[[Category: Vorobiev, S M.]]
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[[Category: Vorobiev, S M]]
[[Category: Actin]]
[[Category: Actin]]
[[Category: Cap g]]
[[Category: Cap g]]

Revision as of 02:10, 25 December 2014

Crystal Structure of Mutant Macrophage Capping Protein (Cap G) with Actin-severing Activity in the Ca2+-Free Form

1j72, resolution 2.50Å

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